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15358-48-2

15358-48-2 structure
15358-48-2 structure
  • Name: 13α-Hydroxylupanine
  • Chemical Name: 13-hydroxylupanine
  • CAS Number: 15358-48-2
  • Molecular Formula: C15H24N2O2
  • Molecular Weight: 264.36300
  • Catalog: Research Areas Cardiovascular Disease
  • Create Date: 2016-05-03 12:36:36
  • Modify Date: 2024-01-02 20:51:48
  • 13-Hydroxylupanine (Hydroxylupanine) is the typical alkaloid profile of sweet lupins.13-Hydroxylupanine blocks ganglionic transmission, decreases cardiac contractility and contracts uterine smooth muscle[1].

Name 13-hydroxylupanine
Synonyms 13-Hydroxylupanin
Alkaloid C 2, from Cadia purpurea
13α-Hydroxylupanine
Description 13-Hydroxylupanine (Hydroxylupanine) is the typical alkaloid profile of sweet lupins.13-Hydroxylupanine blocks ganglionic transmission, decreases cardiac contractility and contracts uterine smooth muscle[1].
Related Catalog
References

[1]. D S Petterson, et al. Disposition of lupanine and 13-hydroxylupanine in man. Xenobiotica. 1994 Sep;24(9):933-41.

Density 1.25g/cm3
Boiling Point 467.7ºC at 760mmHg
Melting Point 169-170°
Molecular Formula C15H24N2O2
Molecular Weight 264.36300
Flash Point 236.6ºC
Exact Mass 264.18400
PSA 43.78000
LogP 0.71830
Vapour Pressure 1.03E-10mmHg at 25°C
Index of Refraction 1.603

CHEMICAL IDENTIFICATION

RTECS NUMBER :
OK5746000
CHEMICAL NAME :
Lupanine, 13-alpha-hydroxy-
CAS REGISTRY NUMBER :
15358-48-2
BEILSTEIN REFERENCE NO. :
0087896
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C15-H24-N2-O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
199 mg/kg
TOXIC EFFECTS :
Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - cyanosis
REFERENCE :
JJATDK JAT, Journal of Applied Toxicology. (John Wiley & Sons Ltd., Baffins Lane, Chichester, W. Sussex PO19 1UD, UK) V.1- 1981- Volume(issue)/page/year: 7,51,1987
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
228 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JAGRAC Journal of Agricultural Research (Washington, DC). (Washington, DC) V.1-78, 1913-49. Discontinued. Volume(issue)/page/year: 32,51,1926
Precursor  0

DownStream  3