13α-Hydroxylupanine

Modify Date: 2024-01-02 20:51:48

13α-Hydroxylupanine structure	Common Name	13α-Hydroxylupanine
	CAS Number	15358-48-2	Molecular Weight	264.36300
	Density	1.25g/cm3	Boiling Point	467.7ºC at 760mmHg
	Molecular Formula	C₁₅H₂₄N₂O₂	Melting Point	169-170°
	MSDS	N/A	Flash Point	236.6ºC

Use of 13α-Hydroxylupanine

13-Hydroxylupanine (Hydroxylupanine) is the typical alkaloid profile of sweet lupins.13-Hydroxylupanine blocks ganglionic transmission, decreases cardiac contractility and contracts uterine smooth muscle[1].

Name	13-hydroxylupanine
Synonym	More Synonyms

Description	13-Hydroxylupanine (Hydroxylupanine) is the typical alkaloid profile of sweet lupins.13-Hydroxylupanine blocks ganglionic transmission, decreases cardiac contractility and contracts uterine smooth muscle[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
References	[1]. D S Petterson, et al. Disposition of lupanine and 13-hydroxylupanine in man. Xenobiotica. 1994 Sep;24(9):933-41.

Density	1.25g/cm3
Boiling Point	467.7ºC at 760mmHg
Melting Point	169-170°
Molecular Formula	C₁₅H₂₄N₂O₂
Molecular Weight	264.36300
Flash Point	236.6ºC
Exact Mass	264.18400
PSA	43.78000
LogP	0.71830
Vapour Pressure	1.03E-10mmHg at 25°C
Index of Refraction	1.603

CHEMICAL IDENTIFICATION

RTECS NUMBER :: OK5746000

CHEMICAL NAME :: Lupanine, 13-alpha-hydroxy-

CAS REGISTRY NUMBER :: 15358-48-2

BEILSTEIN REFERENCE NO. :: 0087896

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C15-H24-N2-O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 199 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - cyanosis

REFERENCE :: JJATDK JAT, Journal of Applied Toxicology. (John Wiley & Sons Ltd., Baffins Lane, Chichester, W. Sussex PO19 1UD, UK) V.1- 1981- Volume(issue)/page/year: 7,51,1987

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 228 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JAGRAC Journal of Agricultural Research (Washington, DC). (Washington, DC) V.1-78, 1913-49. Discontinued. Volume(issue)/page/year: 32,51,1926

Precursor 0
DownStream 3
CAS#:7732-18-5 Water CAS#:550-90-3 15-Oxosparteine CAS#:90-39-1 (-)-Sparteine

13-Hydroxylupanin

Alkaloid C 2, from Cadia purpurea

13α-Hydroxylupanine

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