13α-Hydroxylupanine

Modify Date: 2024-01-02 20:51:48

13α-Hydroxylupanine Structure
13α-Hydroxylupanine structure
Common Name 13α-Hydroxylupanine
CAS Number 15358-48-2 Molecular Weight 264.36300
Density 1.25g/cm3 Boiling Point 467.7ºC at 760mmHg
Molecular Formula C15H24N2O2 Melting Point 169-170°
MSDS N/A Flash Point 236.6ºC

 Use of 13α-Hydroxylupanine


13-Hydroxylupanine (Hydroxylupanine) is the typical alkaloid profile of sweet lupins.13-Hydroxylupanine blocks ganglionic transmission, decreases cardiac contractility and contracts uterine smooth muscle[1].

 Names

Name 13-hydroxylupanine
Synonym More Synonyms

 13α-Hydroxylupanine Biological Activity

Description 13-Hydroxylupanine (Hydroxylupanine) is the typical alkaloid profile of sweet lupins.13-Hydroxylupanine blocks ganglionic transmission, decreases cardiac contractility and contracts uterine smooth muscle[1].
Related Catalog
References

[1]. D S Petterson, et al. Disposition of lupanine and 13-hydroxylupanine in man. Xenobiotica. 1994 Sep;24(9):933-41.

 Chemical & Physical Properties

Density 1.25g/cm3
Boiling Point 467.7ºC at 760mmHg
Melting Point 169-170°
Molecular Formula C15H24N2O2
Molecular Weight 264.36300
Flash Point 236.6ºC
Exact Mass 264.18400
PSA 43.78000
LogP 0.71830
Vapour Pressure 1.03E-10mmHg at 25°C
Index of Refraction 1.603

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
OK5746000
CHEMICAL NAME :
Lupanine, 13-alpha-hydroxy-
CAS REGISTRY NUMBER :
15358-48-2
BEILSTEIN REFERENCE NO. :
0087896
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C15-H24-N2-O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
199 mg/kg
TOXIC EFFECTS :
Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - cyanosis
REFERENCE :
JJATDK JAT, Journal of Applied Toxicology. (John Wiley & Sons Ltd., Baffins Lane, Chichester, W. Sussex PO19 1UD, UK) V.1- 1981- Volume(issue)/page/year: 7,51,1987
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
228 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JAGRAC Journal of Agricultural Research (Washington, DC). (Washington, DC) V.1-78, 1913-49. Discontinued. Volume(issue)/page/year: 32,51,1926

 Precursor & DownStream

Precursor  0

DownStream  3

 Synonyms

13-Hydroxylupanin
Alkaloid C 2, from Cadia purpurea
13α-Hydroxylupanine
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