5466-11-5
5466-11-5 structure
- Name: 2-Chloro-9-(beta-D-ribofuranosyl)purine
- Chemical Name: 2-(2-chloropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
- CAS Number: 5466-11-5
- Molecular Formula: C10H11ClN4O4
- Molecular Weight: 286.67
- Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
- Create Date: 2017-08-26 17:34:43
- Modify Date: 2024-02-01 16:43:02
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2-Chloro-9-(beta-D-ribofuranosyl)purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
| Name | 2-(2-chloropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol |
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| Synonyms |
2-Chloro-purine riboside
(1R)-1-(2-chloro-purin-9-yl)-D-1,4-anhydro-ribitol 2-Cl-nebularine (2R,3R,4S,5R)-2-(2-chloro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol 2-chloro-9-pentofuranosyl-9h-purine (1R)-1-(2-Chlor-purin-9-yl)-D-1,4-anhydro-ribit |
| Description | 2-Chloro-9-(beta-D-ribofuranosyl)purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | |
| References |
| Density | 2.03g/cm3 |
|---|---|
| Boiling Point | 542.7ºC at 760 mmHg |
| Molecular Formula | C10H11ClN4O4 |
| Molecular Weight | 286.67 |
| Flash Point | 282ºC |
| Exact Mass | 286.04700 |
| PSA | 113.52000 |
| Index of Refraction | 1.846 |
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5466-11-5 |
| Literature: Gillerman, Irina; Fischer, Bilha Journal of Medicinal Chemistry, 2011 , vol. 54, # 1 p. 107 - 121 |
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5466-11-5 |
| Literature: Schaeffer; Thomas Journal of the American Chemical Society, 1958 , vol. 80, p. 4896,4898 |
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5466-11-5 |
| Literature: Gillerman, Irina; Fischer, Bilha Journal of Medicinal Chemistry, 2011 , vol. 54, # 1 p. 107 - 121 |
| Precursor 2 | |
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| DownStream 2 | |
