118457-16-2

118457-16-2 structure

Name: (1S)-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]-2-[[(2S)-2-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]-2-hydroxyethyl]amino]ethanol
Chemical Name: (1S)-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]-2-[[(2S)-2-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]-2-hydroxyethyl]amino]ethanol
CAS Number: 118457-16-2
Molecular Formula: C₂₂H₂₅F₂NO₄
Molecular Weight: 405.43500
Create Date: 2016-02-29 03:54:50
Modify Date: 2023-01-16 12:08:10

Name	(1S)-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]-2-[[(2S)-2-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]-2-hydroxyethyl]amino]ethanol
Synonyms	UNII-GMK2E335DQ Levonebivolol l-nebivolol

Density	1.309g/cm3
Boiling Point	600.5ºC at 760mmHg
Molecular Formula	C₂₂H₂₅F₂NO₄
Molecular Weight	405.43500
Flash Point	316.9ºC
Exact Mass	405.17500
PSA	70.95000
LogP	2.75450
Vapour Pressure	2.88E-15mmHg at 25°C
Index of Refraction	1.58

682359-63-3

~60%

118457-16-2

Literature: EGIS GYOGYSZERGYAR RT. Patent: WO2004/41805 A1, 2004 ; Location in patent: Page 68-69 ;

1224567-85-4

~65%

118457-16-2

Literature: ZACH SYSTEM S.P.A.; MARAGNI, Paolo; MICHIELETTO, Ivan; VOLPICELLI, Raffaella; SORIATO, Giorgio; FOLETTO, Johnny; COTARCA, Livius; VERZINI, Massimo Patent: WO2010/49455 A1, 2010 ; Location in patent: Page/Page column 10-11 ;

129050-23-3

905454-41-3

118457-16-2

Literature: WO2008/64826 A1, ; Page/Page column 26-27 ;

Precursor 3
682359-63-3 1224567-85-4 129050-23-3
DownStream 0

56-41-7	108-65-6
56-35-9	64-17-5
67-56-1	108-88-3
141-78-6	1310-73-2
13463-67-7	1333-86-4