746667-48-1
746667-48-1 structure
- Name: BIO-013077-01
- Chemical Name: 6-[5-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl]quinoxaline
- CAS Number: 746667-48-1
- Molecular Formula: C17H13N5
- Molecular Weight: 287.31900
- Create Date: 2018-12-24 10:57:23
- Modify Date: 2024-01-21 21:05:55
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BIO-013077-01 is a pyrazole TGF-β inhibitor[1].
| Name | 6-[5-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl]quinoxaline |
|---|---|
| Synonyms |
6-(3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl)quinoxaline
Quinoxaline |
| Description | BIO-013077-01 is a pyrazole TGF-β inhibitor[1]. |
|---|---|
| Related Catalog | |
| In Vitro | A wide range of cellular functions such as cell proliferation, differentiation, adhesion, migration, and apoptosis are regulated by TGF-β superfamily members. The TGF-βs include the three major TGF-β isoforms, TGF-β1, TGF-β2, and TGF-β3 which are expressed in mammals. TGF-β transduces signals through a complex of two related but structurally and functionally distinct serine/threonine kinase receptors, termed type 1 and type II. Deregulation of TGF-β signaling has been also implicated in various human diseases including cancer, pancreatic diseases, and hematological malignancies[1]. |
| In Vivo | TGF-β Inhibitor |
| References |
| Molecular Formula | C17H13N5 |
|---|---|
| Molecular Weight | 287.31900 |
| Exact Mass | 287.11700 |
| PSA | 67.35000 |
| LogP | 3.39030 |
| HS Code | 2933990090 |
|---|
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |