300851-67-6
300851-67-6 structure
- Name: 4-CMTB
- Chemical Name: 2-(4-Chlorophenyl)-3-methyl-N-(1,3-thiazol-2-yl)butanamide
- CAS Number: 300851-67-6
- Molecular Formula: C14H15ClN2OS
- Molecular Weight: 294.80000
- Catalog: Research Areas Others
- Create Date: 2018-12-29 23:44:15
- Modify Date: 2026-07-16 17:31:24
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4-CMTB is a selective free fatty acid receptor 2 (FFA2/GPR43) agonist and a positive allosteric modulator (pEC50=6.38)[1].
| Name | 2-(4-Chlorophenyl)-3-methyl-N-(1,3-thiazol-2-yl)butanamide |
|---|---|
| Synonyms |
4-CMTB >= (HPLC)
2-(4-Chloro-phenyl)-3-methyl-N-thiazol-2-yl-butyramide 4-Chloro-α-(1-methylethyl)-N-2-thiazolyl-benzeneacetamide (±)-4-CMTB Benzeneacetamide, 4-chloro-α-(1-methylethyl)-N-2-thiazolyl 4-CMTB, 10 mM in DMSO 2-(4-Chlorophenyl)-3-methyl-N-(thiazol-2-yl)butanamide short-chain,4 CMTB,fatty,acids,ECL2,FF,Free Fatty Acid Rector,4CMTB,GPCRs,4-CMTB,ago-allosteric,free,ligand,Inhibitor,inhibit |
| Description | 4-CMTB is a selective free fatty acid receptor 2 (FFA2/GPR43) agonist and a positive allosteric modulator (pEC50=6.38)[1]. |
|---|---|
| Related Catalog | |
| In Vitro | 4-CMTB is both a direct agonist and a positive allosteric modulator of the action of short-chain free fatty acids. 4-CMTB modulates the activity of short-chain fatty acids at FFA2 via the FFA2 second extracellular loop (ECL2)[1][2]. |
| References |
| Molecular Formula | C14H15ClN2OS |
|---|---|
| Molecular Weight | 294.80000 |
| Exact Mass | 294.05900 |
| PSA | 73.72000 |
| LogP | 4.82430 |
| Storage condition | 2-8°C |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H319 |
| Precautionary Statements | P305 + P351 + P338 |
| Hazard Codes | Xi |
| RIDADR | NONH for all modes of transport |
