135247-94-8

135247-94-8 structure

Name: trijuganone C
Chemical Name: methyl 1,6-dimethyl-10,11-dioxo-2,7,8,9-tetrahydro-1H-naphtho[1,2-g][1]benzofuran-6-carboxylate
CAS Number: 135247-94-8
Molecular Formula: C₂₀H₂₀O₅
Molecular Weight: 340.37
Catalog: Signaling Pathways Apoptosis Caspase
Create Date: 2017-03-02 12:12:26
Modify Date: 2024-01-12 12:26:10
Trijuganone C, a natural product extracted from Salvia miltiorrhiza, inhibits the proliferation of cancer cells through induction of apoptosis mediated by mitochondrial dysfunction and caspase activation[1].

Name	methyl 1,6-dimethyl-10,11-dioxo-2,7,8,9-tetrahydro-1H-naphtho[1,2-g][1]benzofuran-6-carboxylate
Synonyms	Phenanthro(1,2-b)furan-6-carboxylic acid,1,2,6,7,8,9,10,11-octahydro-1,6-dimethyl-10,11-dioxo-,methyl ester Trijuganone C

Description	Trijuganone C, a natural product extracted from Salvia miltiorrhiza, inhibits the proliferation of cancer cells through induction of apoptosis mediated by mitochondrial dysfunction and caspase activation[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Apoptosis >> Caspase
Target	caspase
References	[1]. Uto T, et al. Antiproliferative activity and apoptosis induction by trijuganone C isolated from the root of Salvia miltiorrhiza Bunge (Danshen). Phytother Res. 2018 Apr;32(4):657-666.