143157-27-1

143157-27-1 structure

Name: 2′,2′-Difluoro-2′-deoxyuridine 3′,5′-Dibenzoate
Chemical Name: [(2R,5R)-3-benzoyloxy-5-(2,4-dioxopyrimidin-1-yl)-4,4-difluorooxolan-2-yl]methyl benzoate
CAS Number: 143157-27-1
Molecular Formula: C₂₃H₁₈F₂N₂O₇
Molecular Weight: 472.39500
Create Date: 2016-07-15 16:23:07
Modify Date: 2026-07-27 11:32:42

Name	[(2R,5R)-3-benzoyloxy-5-(2,4-dioxopyrimidin-1-yl)-4,4-difluorooxolan-2-yl]methyl benzoate
Synonyms	2'-deoxy-2',2'-difluoro-3,5-dibenzoate-uridine 2'-deoxy-2',2'-difluorouridine-3',5'-dibenzoate 2'-Deoxy-2',2'-difluorouridine 3',5'-dibenzoate ((2R,3R,5R)-3-(benzoyloxy)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4,4-difluorotetrahydrofuran-2-yl)methyl benzoate 3,5-Dibenzoate-2,2-difluorouridine 3',5'-O-di-Benzoyl-2'-difluoro-2'-deoxyuridine Uridine, 2'-deoxy-2',2'-difluoro-, 3',5'-dibenzoate 3',5'-Di-O-benzoyl-2'-deoxy-2',2'-difluorouridine 3',5'-Dibenzoate-2',2'-Difluoro-2'-deoxyuridine Gemcitabine Impurity 30 Ceftobiprole Impurity 8 21-deoxy-21,21-difluoro-3,5-di-O-benzoyl-uridine 2',2'-Difluoro-2'-deoxyuridine 3',5'-Dibenzoate

Density	1.49±0.1 g/cm3(Predicted)
Molecular Formula	C₂₃H₁₈F₂N₂O₇
Molecular Weight	472.39500
Exact Mass	472.10800
PSA	116.95000
LogP	2.56420

1445381-44-1

~83%

143157-27-1

Literature: ALIOS BIOPHARMA, INC.; Beigelman, Leonid; Wang, Guangyi; Smith, David Bernard; Deval, Jerome; Prhavc, Marija Patent: US2013/165400 A1, 2013 ; Location in patent: Paragraph 0418; 0419 ;

908337-63-3

66-22-8

143157-27-1

Literature: DABUR PHARMA LIMITED Patent: WO2006/92808 A1, 2006 ; Location in patent: Page/Page column 44; 45 ;

890044-84-5

10457-14-4

143157-24-8

143157-27-1

Literature: SICOR INC. Patent: WO2006/63105 A1, 2006 ; Location in patent: Page/Page column 11-12 ;

134877-42-2

10457-14-4

143157-24-8

143157-27-1

Literature: Chou; Heath; Patterson; Poteet; Lakin; Hunt Synthesis, 1992 , # 6 p. 565 - 570

122111-03-9

143157-27-1

Literature: ALIOS BIOPHARMA, INC.; Beigelman, Leonid; Wang, Guangyi; Smith, David Bernard; Deval, Jerome; Prhavc, Marija Patent: US2013/165400 A1, 2013 ;

Precursor 4
66-22-8 10457-14-4 134877-42-2 122111-03-9
DownStream 1
114248-23-6

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