177744-96-6
177744-96-6 structure
- Name: LY88074
- Chemical Name: (4-hydroxyphenyl)-[3-(4-hydroxyphenyl)-1-benzothiophen-2-yl]methanone
- CAS Number: 177744-96-6
- Molecular Formula: C21H14O4S
- Molecular Weight: 346.39900
- Catalog: Research Areas Endocrinology
- Create Date: 2017-06-26 14:09:14
- Modify Date: 2024-01-05 21:12:01
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LY88074 (Compound 88074) is a Raloxifene analog lacking the basic side chain. Raloxifene is a selective estrogen receptor modulator, and reduces fracture risk at least in part by improving the mechanical properties of bone in a cell- and estrogen receptor-independent manner[1].
| Name | (4-hydroxyphenyl)-[3-(4-hydroxyphenyl)-1-benzothiophen-2-yl]methanone |
|---|
| Description | LY88074 (Compound 88074) is a Raloxifene analog lacking the basic side chain. Raloxifene is a selective estrogen receptor modulator, and reduces fracture risk at least in part by improving the mechanical properties of bone in a cell- and estrogen receptor-independent manner[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Removal of the aminoethylpiperdine moiety, as in LY88074 (Compound 88074), reduces bone binding, compared to Raloxifene. The interaction of LY88074 with collagen matrix, although significant, is less than the interaction found with Raloxifene[1]. |
| References |
| Molecular Formula | C21H14O4S |
|---|---|
| Molecular Weight | 346.39900 |
| Exact Mass | 346.06600 |
| PSA | 85.77000 |
| LogP | 5.21050 |