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62921-74-8

62921-74-8 structure
62921-74-8 structure
  • Name: m-PEG3-Tos
  • Chemical Name: 2-[2-(2-methoxyethoxy)ethoxy]ethanol,4-methylbenzenesulfonic acid
  • CAS Number: 62921-74-8
  • Molecular Formula: C14H22O6S
  • Molecular Weight: 336.401
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2016-07-16 20:00:27
  • Modify Date: 2025-08-27 18:39:15
  • m-PEG3-Tos is a PEG-based PROTAC linker can be used in the synthesis of Silymarin (HY-W043277)[1].

Name 2-[2-(2-methoxyethoxy)ethoxy]ethanol,4-methylbenzenesulfonic acid
Synonyms 3,6,9-trioxadecyl tosylate
2-[2-(2-Methoxyethoxy)ethoxy]ethanol - 4-methylbenzenesulfonic acid (1:1)
CH3(OCH2CH2)3OTs
Ethanol, 2-[2-(2-methoxyethoxy)ethoxy]-, compd. with 4-methylbenzenesulfonic acid (1:1)
Ethanol,2-[2-(2-methoxyethoxy)ethoxy]-,4-methylbenzenesulfonate
CH3OC2H4OC2H4OC2H4OTs
2-[2-(2-Methoxyethoxy)ethoxy]ethyl 4-methylbenzenesulfonate
triethyleneglycol monotosylate
triethylene glycol methyl tosyl ether
triethyleneglycol monomethyl ether tosylate
Description m-PEG3-Tos is a PEG-based PROTAC linker can be used in the synthesis of Silymarin (HY-W043277)[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Yuxia Zhao, et al. Derivative of silybin ethers, and synthetic method and application thereof. Patent CN105037337A.

Molecular Formula C14H22O6S
Molecular Weight 336.401
Flash Point 215 °C
Exact Mass 336.124268
PSA 110.67000
LogP 1.98080
Index of Refraction 1.53
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