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62921-76-0

62921-76-0 structure
62921-76-0 structure
  • Name: m-PEG4-Tos
  • Chemical Name: 2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethanol,4-methylbenzenesulfonic acid
  • CAS Number: 62921-76-0
  • Molecular Formula: C16H26O7S
  • Molecular Weight: 380.45400
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2017-03-16 13:46:26
  • Modify Date: 2024-01-10 13:34:28
  • m-PEG4-Tos is a derivative of silybin ethers, extracted from patent CN105037337A (compound III-b). m-PEG4-Tos is a PEG-based PROTAC linker can be used in the synthesis of Silymarin (HY-W043277)[1].

Name 2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethanol,4-methylbenzenesulfonic acid
Synonyms 2-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}ethyl 4-methylbenzenesulfonate
toluene-4-sulfonic acid 2-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}ethyl ester
2,5,8,11-Tetraoxatridecan-13-ol,4-methylbenzenesulfonate
CH3(OCH2CH2)4OTs
CH3[O(CH2)2]4OTs
(2,5,8,11-tetraoxatridecan-13-yl) p-toluenesulfonate
2,5,8,11-tetraoxatridecan-13-ol tosylate
Description m-PEG4-Tos is a derivative of silybin ethers, extracted from patent CN105037337A (compound III-b). m-PEG4-Tos is a PEG-based PROTAC linker can be used in the synthesis of Silymarin (HY-W043277)[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Yuxia Zhao, et al. Derivative of silybin ethers, and synthetic method and application thereof. Patent CN105037337A.

Molecular Formula C16H26O7S
Molecular Weight 380.45400
Exact Mass 380.15000
PSA 119.90000
LogP 1.99740
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