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1056459-37-0

1056459-37-0 structure
1056459-37-0 structure
  • Name: Prasugrel chloride impurity
  • Chemical Name: [5-[5-chloro-1-(2-fluorophenyl)-2-oxopentyl]-6,7-dihydro-4H-thieno[3,2-c]pyridin-2-yl] acetate
  • CAS Number: 1056459-37-0
  • Molecular Formula: C20H21ClFNO3S
  • Molecular Weight: 409.902
  • Catalog: Research Areas Others
  • Create Date: 2017-04-10 00:33:53
  • Modify Date: 2024-01-02 11:58:28
  • Prasugrel chloride impurity is a catp impurity of Prasugrel, exacted from patent US20130345428A1, line 0053. Prasugrel is an orally active and potent P2Y12 receptor antagonist, and inhibits ADP-induced platelet aggregation[1][2].

Name [5-[5-chloro-1-(2-fluorophenyl)-2-oxopentyl]-6,7-dihydro-4H-thieno[3,2-c]pyridin-2-yl] acetate
Synonyms 2-Pentanone, 1-[2-(acetyloxy)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl]-5-chloro-1-(2-fluorophenyl)-
5-[5-Chloro-1-(2-fluorophenyl)-2-oxopentyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate
Description Prasugrel chloride impurity is a catp impurity of Prasugrel, exacted from patent US20130345428A1, line 0053. Prasugrel is an orally active and potent P2Y12 receptor antagonist, and inhibits ADP-induced platelet aggregation[1][2].
Related Catalog
References

[1]. Hiroyuki Miyata, et al. Method for production of prasugrel hydrochloride having high purity. US20130345428A1.

[2]. Sugidachi A, et al. The greater in vivo antiplatelet effects of prasugrel as compared to clopidogrel reflect more efficient generation of its active metabolite with similar antiplatelet activity to that of clopidogrel's active metabolite. J Thromb Haemost. 2007 Jul;5(7):1545-51.

Density 1.3±0.1 g/cm3
Boiling Point 522.6±50.0 °C at 760 mmHg
Molecular Formula C20H21ClFNO3S
Molecular Weight 409.902
Flash Point 269.8±30.1 °C
Exact Mass 409.091461
PSA 74.85000
LogP 3.79
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.583
HS Code 2934999090
HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%