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96517-92-9

96517-92-9 structure
96517-92-9 structure
  • Name: Bis-PEG3-acid
  • Chemical Name: 3,3'-[oxybis(ethane-2,1-diyloxy)]dipropanoic acid
  • CAS Number: 96517-92-9
  • Molecular Formula: C10H18O7
  • Molecular Weight: 250.24600
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2016-03-01 05:07:05
  • Modify Date: 2024-01-05 08:14:14
  • Bis-PEG3-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

Name 3,3'-[oxybis(ethane-2,1-diyloxy)]dipropanoic acid
Synonyms 4,7,10-trioxa-tridecanedioic acid
4,7,10-Trioxa-tridecandisaeure
Description Bis-PEG3-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Zhao Q, et al. Discovery of SIAIS178 as an Effective BCR-ABL Degrader by Recruiting Von Hippel-Lindau (VHL) E3 Ubiquitin Ligase. J Med Chem. 2019 Oct 24;62(20):9281-9298.

Molecular Formula C10H18O7
Molecular Weight 250.24600
Exact Mass 250.10500
PSA 102.29000
Hazard Codes Xi