98774-23-3
98774-23-3 structure
- Name: Tesmilifene
- Chemical Name: Tesmilifene
- CAS Number: 98774-23-3
- Molecular Formula: C19H25NO
- Molecular Weight: 283.408
- Catalog: API Antiparasitic drug Antimalarial
- Create Date: 2018-07-18 19:47:07
- Modify Date: 2025-08-23 16:34:51
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Tesmilifene is a novel agent that augments cytotoxicity of various chemotherapeutic agents both in vitro and in vivo. It binds selectively to the high-affinity microsomal antiestrogen binding site (Ki=50nm) but has no affinity for estrogen receptors. Inhi
| Name | Tesmilifene |
|---|---|
| Synonyms |
DPPE
UNII-I43T3ID6G2 (2-(4-benzylphenoxy)ethyl)diethylamine Ethanamine, N,N-diethyl-2-[4-(phenylmethyl)phenoxy]- tesmilifene 2-(4-Benzylphenoxy)-N,N-diethylethanamine 2-[(a-Phenyl-p-tolyl)oxy]triethylamine Depmpe |
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 397.0±30.0 °C at 760 mmHg |
| Molecular Formula | C19H25NO |
| Molecular Weight | 283.408 |
| Flash Point | 116.8±26.9 °C |
| Exact Mass | 283.193604 |
| PSA | 12.47000 |
| LogP | 5.04 |
| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
| Index of Refraction | 1.543 |
|
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98774-23-3 |
| Literature: Journal of Medicinal Chemistry, , vol. 43, # 4 p. 721 - 735 |
|
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98774-23-3 |
| Literature: Rev. Asoc. bioquim. arg., , vol. 20, p. 7,12 Rev. Fac. Cienc. quim. Univ. La Plata, , vol. 22, p. 143,147 |
