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81732-46-9

81732-46-9 structure
81732-46-9 structure
  • Name: Bambuterol Hydrochloride
  • Chemical Name: bambuterol hydrochloride
  • CAS Number: 81732-46-9
  • Molecular Formula: C18H30ClN3O5
  • Molecular Weight: 403.901
  • Catalog: API Respiratory medication Asthma
  • Create Date: 2018-07-18 21:37:11
  • Modify Date: 2024-01-02 09:02:40
  • Bambuterol Hcl is a long acting beta-adrenoceptor agonist (LABA) used in the treatment of asthma; it also is a prodrug of terbutaline.IC50 value:Target: beta-adrenoceptor agonistBambuterol is contraindicated in pregnancy and in people with seriously impaired liver function. It can be used by people with renal impairment, but dose adjustments are necessary. The adverse effect profile of bambuterol is similar to that of salbutamol, and may include fatigue, nausea, palpitations, headache, dizziness and tremor.

Name bambuterol hydrochloride
Synonyms (±)-Bambuterol hydrochloride
[3-[2-(tert-butylamino)-1-hydroxyethyl]-5-(dimethylcarbamoyloxy)phenyl] N,N-dimethylcarbamate,hydrochloride
Bambuterol hydrochloride
5-[2-(tert-Butylamino)-1-hydroxyethyl]-1,3-phenylene bis(dimethylcarbamate) hydrochloride (1:1)
5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-diyl bis(dimethylcarbamate) hydrochloride (1:1)
Carbamic acid, N,N-dimethyl-, 5-[2-[(1,1-dimethylethyl)amino]-1-hydroxyethyl]-1,3-phenylene ester, hydrochloride (1:1)
5-{1-Hydroxy-2-[(2-methyl-2-propanyl)amino]ethyl}-1,3-phenylene bis(dimethylcarbamate) hydrochloride (1:1)
UNII:786Q84QZ3F
MFCD03427293
Bambec
Bambuterol (hydrochloride)
Description Bambuterol Hcl is a long acting beta-adrenoceptor agonist (LABA) used in the treatment of asthma; it also is a prodrug of terbutaline.IC50 value:Target: beta-adrenoceptor agonistBambuterol is contraindicated in pregnancy and in people with seriously impaired liver function. It can be used by people with renal impairment, but dose adjustments are necessary. The adverse effect profile of bambuterol is similar to that of salbutamol, and may include fatigue, nausea, palpitations, headache, dizziness and tremor.
Related Catalog
References

[1]. Bambuterol, From Wikipedia

Density 1.154g/cm3
Boiling Point 500.9ºC at 760 mmHg
Melting Point 222-224ºC
Molecular Formula C18H30ClN3O5
Molecular Weight 403.901
Flash Point 256.7ºC
Exact Mass 403.187408
PSA 91.34000
LogP 3.42180
Index of Refraction 1.533
Storage condition -20°C Freezer
Water Solubility H2O: ~33 mg/mL, soluble
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3