220810-26-4

220810-26-4 structure

Name: (Des-Gly10,D-His(Bzl)6,Pro-NHEt9)-LHRH acetate salt
Chemical Name: histrelin acetate
CAS Number: 220810-26-4
Molecular Formula: C₆₆H₈₆N₁₈O_12.xC₂H₄O₂
Molecular Weight: 1323.50 (free base)
Catalog: Biochemical Peptide
Create Date: 2017-10-16 21:58:17
Modify Date: 2026-07-14 13:10:05
Histrelin acetate, a GnRH analogue, is a GnRH Receptor agonist. Histrelin acetate increases serum luteinising hormone (LH), follicle stimulating hormone (FSH) and testosterone levels. Histrelin acetate can be used in the research of prostate cancer, endometriosis[1][2][5].

Name	histrelin acetate
Synonyms	Vantas //BP (Des-Gly10,D-His(Bzl)6,Pro-NHEt 9)-LHRH acetate salt Pyr-His-Trp-Ser-Tyr-D-His(Bzl)-Leu-g-Pro-NHEt acetate salt Supprelin la Vantas Histrelin Acetate(acetate) (Des-Gly,D-His(Bzl),Pro-NHEt)-LHRH acetate salt Histrelin acetate, >= HistrelinAcetate impurity (Des-Gly10,D-His(Bzl)6,Pro-NHEt 9)-LHRH acetate

Description	Histrelin acetate, a GnRH analogue, is a GnRH Receptor agonist. Histrelin acetate increases serum luteinising hormone (LH), follicle stimulating hormone (FSH) and testosterone levels. Histrelin acetate can be used in the research of prostate cancer, endometriosis[1][2][5].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> GNRH Receptor Research Areas >> Cancer
References	[1]. Emma D Deeks, et al. Histrelin: in advanced prostate cancer. Drugs. 2010 Mar 26;70(5):623-30. [2]. Marlena Juszczak, et al. Hypothalamic gonadotropin-releasing hormone receptor activation stimulates oxytocin release from the rat hypothalamo-neurohypophysial system while melatonin inhibits this process. Brain Res Bull. 2010 Jan 15;81(1):185-90. [3]. P E Cohen, et al. Colony-stimulating factor-1 plays a major role in the development of reproductive function in male mice. Mol Endocrinol. 1997 Oct;11(11):1636-50. [4]. D W Hahn, et al. Development of an animal model for quantitatively evaluating effects of drugs on endometriosis. Fertil Steril. 1985 Sep;44(3):410-5. [5]. E Boczek-Leszczyk, et al. Vasopressin release from the rat hypothalamo-neurohypophysial system: effects of gonadotrophin-releasing hormone (GnRH), its analogues and melatonin. J Physiol Pharmacol. 2010 Aug;61(4):459-66.