(Des-Gly10,D-His(Bzl)6,Pro-NHEt9)-LHRH acetate salt

Modify Date: 2025-08-25 22:23:17

(Des-Gly10,D-His(Bzl)6,Pro-NHEt9)-LHRH acetate salt structure	Common Name	(Des-Gly10,D-His(Bzl)6,Pro-NHEt9)-LHRH acetate salt
	CAS Number	220810-26-4	Molecular Weight	1323.50 (free base)
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₆₆H₈₆N₁₈O_12.xC₂H₄O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of (Des-Gly10,D-His(Bzl)6,Pro-NHEt9)-LHRH acetate salt

Histrelin acetate, a GnRH analogue, is a GnRH Receptor agonist. Histrelin acetate increases serum luteinising hormone (LH), follicle stimulating hormone (FSH) and testosterone levels. Histrelin acetate can be used in the research of prostate cancer, endometriosis[1][2][5].

Name	histrelin acetate

Description	Histrelin acetate, a GnRH analogue, is a GnRH Receptor agonist. Histrelin acetate increases serum luteinising hormone (LH), follicle stimulating hormone (FSH) and testosterone levels. Histrelin acetate can be used in the research of prostate cancer, endometriosis[1][2][5].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> GNRH Receptor Research Areas >> Cancer
References	[1]. Emma D Deeks, et al. Histrelin: in advanced prostate cancer. Drugs. 2010 Mar 26;70(5):623-30. [2]. Marlena Juszczak, et al. Hypothalamic gonadotropin-releasing hormone receptor activation stimulates oxytocin release from the rat hypothalamo-neurohypophysial system while melatonin inhibits this process. Brain Res Bull. 2010 Jan 15;81(1):185-90. [3]. P E Cohen, et al. Colony-stimulating factor-1 plays a major role in the development of reproductive function in male mice. Mol Endocrinol. 1997 Oct;11(11):1636-50. [4]. D W Hahn, et al. Development of an animal model for quantitatively evaluating effects of drugs on endometriosis. Fertil Steril. 1985 Sep;44(3):410-5. [5]. E Boczek-Leszczyk, et al. Vasopressin release from the rat hypothalamo-neurohypophysial system: effects of gonadotrophin-releasing hormone (GnRH), its analogues and melatonin. J Physiol Pharmacol. 2010 Aug;61(4):459-66.

Description

Related Catalog

Signaling Pathways >> GPCR/G Protein >> GNRH Receptor

Research Areas >> Cancer

References

[1]. Emma D Deeks, et al. Histrelin: in advanced prostate cancer. Drugs. 2010 Mar 26;70(5):623-30.

[2]. Marlena Juszczak, et al. Hypothalamic gonadotropin-releasing hormone receptor activation stimulates oxytocin release from the rat hypothalamo-neurohypophysial system while melatonin inhibits this process. Brain Res Bull. 2010 Jan 15;81(1):185-90.

[3]. P E Cohen, et al. Colony-stimulating factor-1 plays a major role in the development of reproductive function in male mice. Mol Endocrinol. 1997 Oct;11(11):1636-50.

[4]. D W Hahn, et al. Development of an animal model for quantitatively evaluating effects of drugs on endometriosis. Fertil Steril. 1985 Sep;44(3):410-5.

[5]. E Boczek-Leszczyk, et al. Vasopressin release from the rat hypothalamo-neurohypophysial system: effects of gonadotrophin-releasing hormone (GnRH), its analogues and melatonin. J Physiol Pharmacol. 2010 Aug;61(4):459-66.

Molecular Formula	C₆₆H₈₆N₁₈O_12.xC₂H₄O₂
Molecular Weight	1323.50 (free base)
Exact Mass	1442.71000
PSA	521.46000
LogP	3.97960
InChIKey	OWAUGAMNPZHEOJ-YKZVIGSYSA-N
SMILES	CC(=O)O.CCNC(=O)C1CCCN1C(=O)C(CCCN=C(N)N)NC(=O)C(CC(C)C)NC(=O)C(Cc1cn(Cc2ccccc2)cn1)NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(CO)NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(Cc1cnc[nH]1)NC(=O)C1CCC(=O)N1

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Histrelin (acetate)
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Histrelin acetate
Price: $1200.0/250mg $2600.0/1g $750.0/100mg
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: Histrelin (acetate)
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

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Price: ￥1000/1 mg

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(Des-Gly10,D-His(Bzl)6,Pro-NHEt9)-LHRH acetate salt

Use of (Des-Gly10,D-His(Bzl)6,Pro-NHEt9)-LHRH acetate salt

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