Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Mecarbinate
Price: ￥106.0/5g ￥1016.0/100g ￥356.0/25g ￥176.0/10g
Purity: 98.0%
Stocking Period: 2 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Mecarbinate
Price: $250.0/100mg $300.0/250mg $1000.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Ethyl 5-hydroxy-1,2-dimethyl-1H-indole-3-carboxylate
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Henan Tianfu Chemical Co., Ltd.
China
Product Name: 15574-49-9 Mecarbinate
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

15574-49-9

15574-49-9 structure

Name: Mecarbinate
Chemical Name: Ethyl 1,2-Dimethyl-5-Hydroxyindole-3-Carboxylate
CAS Number: 15574-49-9
Molecular Formula: C₁₃H₁₅NO₃
Molecular Weight: 233.263
Catalog: Signaling Pathways Anti-infection HCV
Create Date: 2018-06-08 22:16:53
Modify Date: 2024-01-02 20:57:52
Mecarbinate is an anti-hepatitis C virus (HCV) agent.

Name	Ethyl 1,2-Dimethyl-5-Hydroxyindole-3-Carboxylate
Synonyms	1,2-Dimethyl-5-hydroxyindole-3-Carboxylate Ethyl Mecarbine MFCD00451373 5-Hydroxy-1,2-dimethylindole-3-carboxylic Acid Ethyl Ester Ethyl 5-Hydroxy-1,2-dimethylindole-3-carboxylate 1,2-Dimethyl-5-hydroxyindole-2-Carboxylate Ethyl 1H-Indole-3-carboxylic acid, 5-hydroxy-1,2-dimethyl-, ethyl ester Ethyl 5-hydroxy-1,2-dimethyl-1H-indole-3-carboxylate Mecarbinate

Description	Mecarbinate is an anti-hepatitis C virus (HCV) agent.
Related Catalog	Signaling Pathways >> Anti-infection >> HCV Research Areas >> Infection Natural Products >> Phenols
Target	HCV
References	[1]. Andreev IA, et al. Discovery of the 2-phenyl-4,5,6,7-Tetrahydro-1H-indole as a novel anti-hepatitis C virus targeting scaffold. Eur J Med Chem. 2015;96:250-8.

Density	1.2±0.1 g/cm3
Boiling Point	399.8±37.0 °C at 760 mmHg
Melting Point	208-212ºC
Molecular Formula	C₁₃H₁₅NO₃
Molecular Weight	233.263
Flash Point	195.6±26.5 °C
Exact Mass	233.105194
PSA	51.46000
LogP	2.77
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.572

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NL6003600

CHEMICAL NAME :: 1H-Indole-3-carboxylic acid, 5-hydroxy-1,2-dimethyl-, ethyl ester

CAS REGISTRY NUMBER :: 15574-49-9

BEILSTEIN REFERENCE NO. :: 0193275

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C13-H15-N-O3

MOLECULAR WEIGHT :: 233.29

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia) History Unknown Volume(issue)/page/year: (1),29,1994

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia) History Unknown Volume(issue)/page/year: (1),29,1994

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia) History Unknown Volume(issue)/page/year: (1),29,1994

Hazard Codes	Xi: Irritant;
HS Code	2933990090

21759-70-6

106-51-4

15574-49-9

Literature: EP1731506 A1, ; Page/Page column 12; 16 ;

141-97-9

74-89-5

106-51-4

15574-49-9

Literature: Journal of Medicinal Chemistry, , vol. 45, # 14 p. 3094 - 3102

870-85-9

106-51-4

15574-49-9

Literature: Journal of Organic Chemistry, , vol. 24, p. 1750 US2852527 , ;

21759-71-7

106-51-4

~90%

15574-49-9

Literature: Velezheva, Valeriya S.; Kornienko, Albert G.; Topilin, Sergey V.; Turashev, Ascar D.; Peregudov, Alexander S.; Brennan, Patrick J. Journal of Heterocyclic Chemistry, 2006 , vol. 43, # 4 p. 873 - 879

21759-71-7

106-51-4

~0%

7287-40-3

15574-49-9

Detail

870-85-9

67-64-1

106-51-4

15574-49-9

Literature: Zhurnal Obshchei Khimii, , vol. 25, p. 1355; engl. Ausg. S. 1301

Precursor 7
21759-70-6 106-51-4 141-97-9 74-89-5
870-85-9 21759-71-7 67-64-1
DownStream 3
105909-93-1 40945-79-7 40963-98-2

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

56-41-7	108-65-6
56-35-9	64-17-5
67-56-1	108-88-3
141-78-6	1310-73-2
13463-67-7	1333-86-4