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436-05-5

436-05-5 structure
436-05-5 structure
  • Name: Curine
  • Chemical Name: curine
  • CAS Number: 436-05-5
  • Molecular Formula: C36H38N2O6
  • Molecular Weight: 594.697
  • Catalog: Biochemical Chinese herbal medicine ingredients
  • Create Date: 2018-02-24 08:00:00
  • Modify Date: 2024-01-08 17:11:04
  • (-)-Curine is an orally active bisbenzylisoquinoline alkaloid isolated from Chondrodendron platyphyllum. (-)-Curine presents anti-inflammatory and analgesic effects at nontoxic doses, at least in part, resulting from the inhibition of prostaglandin E2 production[1].

Name curine
Synonyms Chondodendrine
1-Curine
l-Curine
Einecs 207-109-4
(1β)-6,6'-Dimethoxy-2,2'-dimethyltubocuraran-7',12'-diol
(-)-BEBEERINE
1-Bebeerine
Chonodoendrine (L)
L-BEBEERINE
d-bebeerine
(+-)-chondrodendrine
Description (-)-Curine is an orally active bisbenzylisoquinoline alkaloid isolated from Chondrodendron platyphyllum. (-)-Curine presents anti-inflammatory and analgesic effects at nontoxic doses, at least in part, resulting from the inhibition of prostaglandin E2 production[1].
Related Catalog
Target

EP2

References

[1]. Leite FC, et al. Curine, an alkaloid isolated from Chondrodendron platyphyllum inhibits prostaglandin E2 in experimental models of inflammation and pain. Planta Med. 2014 Aug;80(13):1072-8.

Density 1.2±0.1 g/cm3
Boiling Point 706.5±60.0 °C at 760 mmHg
Melting Point 213°; mp 221° in vacuo; mp 161°
Molecular Formula C36H38N2O6
Molecular Weight 594.697
Flash Point 381.1±32.9 °C
Exact Mass 594.273010
PSA 83.86000
LogP 4.12
Vapour Pressure 0.0±2.3 mmHg at 25°C
Index of Refraction 1.620
Storage condition 2-8℃
Hazard Codes T+: Very toxic;
Risk Phrases R26/27/28
Safety Phrases 22-36/37/39-45
RIDADR UN 1544
WGK Germany 3
Precursor  0

DownStream  3