Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: levomepromazine hydrochloride
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Purity: 98.0%
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1236-99-3

1236-99-3 structure

1236-99-3 structure

Name: Levomepromazine hydrochloride
Chemical Name: Levomepromazine hydrochloride
CAS Number: 1236-99-3
Molecular Formula: C₁₉H₂₅ClN₂OS
Molecular Weight: 364.93300
Catalog: analytical chemistry Standard Pharmacopoeia Standards and Magazine Standards
Create Date: 2018-09-23 12:11:57
Modify Date: 2024-04-02 12:47:09

Name	Levomepromazine hydrochloride
Synonyms	methotrimeprazine hydrochloride Levopromazine hydrochloride Einecs 214-978-3 (R)-3-(2-Methoxy-10H-phenothiazin-10-yl)-N,N,2-trimethylpropylamine hydrochloride Levomepromazinium chloride 7044 Rp hydrochloride LevomepromazineHCl

Boiling Point	468ºC at 760 mmHg
Molecular Formula	C₁₉H₂₅ClN₂OS
Molecular Weight	364.93300
Flash Point	236.8ºC
Exact Mass	364.13800
PSA	41.01000
LogP	5.36260
Vapour Pressure	6.22E-09mmHg at 25°C
Storage condition	2-8°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SO6150000

CHEMICAL NAME :: Phenothiazine, 10-(3-(dimethylamino)-2-methylpropyl)-2-methoxy-, hydrochloride

CAS REGISTRY NUMBER :: 1236-99-3

LAST UPDATED :: 199707

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C19-H24-N2-O-S.Cl-H

MOLECULAR WEIGHT :: 364.97

WISWESSER LINE NOTATION :: T C666 BN ISJ B1Y1&1N1&1 EO1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 380 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CKFRAY Ceskoslovenska Farmacie. (PNS-Ustredni Expedice a Dovoz Tisku, Kafkova 19, 160 00 Prague 6, Czechoslovakia) V.1- 1952- Volume(issue)/page/year: 15,455,1966

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 135 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1849- Volume(issue)/page/year: 160,1852,1966

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 360 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1849- Volume(issue)/page/year: 155,1029,1961

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 75 mg/kg

TOXIC EFFECTS :: Behavioral - sleep

REFERENCE :: APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 19,87,1962