1236-99-3

• 常用中文名：左美丙嗪盐酸盐
• 常用英文名：Levomepromazine hydrochloride
• CAS号：1236-99-3
• 分子式：C₁₉H₂₅ClN₂OS
• 分子量：364.93300
• 相关类别： 分析化学 标准品 药典标准品和杂志标准品
• 发布时间：2018-09-23 12:11:57
• 更新时间：2024-04-02 12:47:09

名称

• 中文名: 左美丙嗪盐酸盐
• 英文名: Levomepromazine hydrochloride
• 中文别名: 10-(3-二甲基氨基-2-甲基丙基)-2-甲氧基吩噻嗪盐酸盐
• 英文别名: methotrimeprazine hydrochloride; Levopromazine hydrochloride; Einecs 214-978-3; (R)-3-(2-Methoxy-10H-phenothiazin-10-yl)-N,N,2-trimethylpropylamine hydrochloride; Levomepromazinium chloride; 7044 Rp hydrochloride; LevomepromazineHCl

物化性质

• 沸点: 468ºC at 760 mmHg
• 分子式: C₁₉H₂₅ClN₂OS
• 分子量: 364.93300
• 闪点: 236.8ºC
• 精确质量: 364.13800
• PSA: 41.01000
• LogP: 5.36260
• 蒸汽压: 6.22E-09mmHg at 25°C
• 储存条件: 2-8°C

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : SO6150000 CHEMICAL NAME : Phenothiazine, 10-(3-(dimethylamino)-2-methylpropyl)-2-methoxy-, hydrochloride CAS REGISTRY NUMBER : 1236-99-3 LAST UPDATED : 199707 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C19-H24-N2-O-S.Cl-H MOLECULAR WEIGHT : 364.97 WISWESSER LINE NOTATION : T C666 BN ISJ B1Y1&1N1&1 EO1 &GH HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 380 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CKFRAY Ceskoslovenska Farmacie. (PNS-Ustredni Expedice a Dovoz Tisku, Kafkova 19, 160 00 Prague 6, Czechoslovakia) V.1- 1952- Volume(issue)/page/year: 15,455,1966 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 135 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1849- Volume(issue)/page/year: 160,1852,1966 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 360 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1849- Volume(issue)/page/year: 155,1029,1961 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 75 mg/kg TOXIC EFFECTS : Behavioral - sleep REFERENCE : APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 19,87,1962