107233-08-9
107233-08-9 structure
- Name: Cevimeline
- Chemical Name: cevimeline
- CAS Number: 107233-08-9
- Molecular Formula: C10H17NOS
- Molecular Weight: 199.31
- Catalog: Signaling Pathways GPCR/G Protein mAChR
- Create Date: 2018-09-26 18:22:59
- Modify Date: 2024-01-02 17:34:05
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Cevimeline (Evoxac) is a parasympathomimetic and muscarinic agonist, with particular effect on M3 receptors; used in the treatment of dry mouth associated with sjogren's syndrome.IC50 value:Target: M3 receptor
| Name | cevimeline |
|---|---|
| Synonyms |
3]oxathiolane]
CevimelineHClSalt CEVIMELINE, HYDROCHLORIDE SALT (2R,2'R)-2'-Methylspiro[4-azabicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane] cis-2'-Methylspiro[4-azabicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane] Evoxac AF-102B (2R,2'R)-2'-Methylspiro[4-azabicyclo[2.2.2]octan-2,5'-[1,3]oxathiolan] (2R,2'R)-Cevimeline Cevimeline (2R,2'R)-rel-2'-Methylspiro[4-azabicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane] 3R)-rel Spiro[1-azabicyclo[2.2.2]octane-3,5'-[1,3]oxathiolane], 2'-methyl-, (2'R,3R)- SNI-2011 |
| Description | Cevimeline (Evoxac) is a parasympathomimetic and muscarinic agonist, with particular effect on M3 receptors; used in the treatment of dry mouth associated with sjogren's syndrome.IC50 value:Target: M3 receptor |
|---|---|
| Related Catalog | |
| References |
[4]. Voskoboynik B, et al.Cevimeline (Evoxac) overdose.J Med Toxicol. 2011 Mar;7(1):57-9. |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 308.5±42.0 °C at 760 mmHg |
| Melting Point | 195-197ºC |
| Molecular Formula | C10H17NOS |
| Molecular Weight | 199.31 |
| Flash Point | 140.4±27.9 °C |
| PSA | 37.77000 |
| LogP | 1.23 |
| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
| Index of Refraction | 1.586 |
| Storage condition | -20°C |