DC Chemicals Limited
China
Product Name: Methyl 2,5-dihydroxycinnamate
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Methyl 2,5-dihydroxycinnamate
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

63177-57-1

63177-57-1 structure

63177-57-1 structure

Name: Methyl (2E)-3-(2,5-dihydroxyphenyl)acrylate
Chemical Name: Methyl 2,5-Dihydroxycinnamate
CAS Number: 63177-57-1
Molecular Formula: C₁₀H₁₀O₄
Molecular Weight: 194.184
Catalog: Flavors and spices Synthetic spice Aromatic cinnamic acid, esters and derivatives
Create Date: 2018-02-19 08:00:00
Modify Date: 2024-01-30 18:04:26
Methyl 2,5-dihydroxycinnamate is an erbstatin analog and a stable, potent inhibitor of EGFR kinase activity[1].

Name	Methyl 2,5-Dihydroxycinnamate
Synonyms	2-Propenoic acid, 3-(2,5-dihydroxyphenyl)-, methyl ester, (2E)- Methyl (2E)-3-(2,5-dihydroxyphenyl)acrylate MFCD00132932 methyl (E)-3-(2,5-dihydroxyphenyl)prop-2-enoate

Description	Methyl 2,5-dihydroxycinnamate is an erbstatin analog and a stable, potent inhibitor of EGFR kinase activity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> EGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR
References	[1]. Umezawa K, et al. Inhibition of epidermal growth factor-induced DNA synthesis by tyrosine kinase inhibitors. FEBS Lett. 1990 Jan 29;260(2):198-200.

Density	1.3±0.1 g/cm3
Boiling Point	400.7±35.0 °C at 760 mmHg
Melting Point	178-180°C
Molecular Formula	C₁₀H₁₀O₄
Molecular Weight	194.184
Flash Point	163.3±19.4 °C
Exact Mass	194.057907
PSA	66.76000
LogP	1.51
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.629
Storage condition	−20°C
Water Solubility	0.1 M NaOH: soluble

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H315-H319-H335
Precautionary Statements	P301 + P312 + P330-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes	T: Toxic;
Risk Phrases	R23/24/25
Safety Phrases	S22-S26-S36-S45
RIDADR	NONH for all modes of transport
WGK Germany	3