88515-58-6

88515-58-6 structure

Name: Rosamultin
Chemical Name: Rosamultin
CAS Number: 88515-58-6
Molecular Formula: C₃₆H₅₈O₁₀
Molecular Weight: 650.84000
Catalog: Signaling Pathways Metabolic Enzyme/Protease HIV Protease
Create Date: 2018-10-17 18:07:44
Modify Date: 2024-01-23 16:31:53
Rosamultin is a 19 α-hydroxyursane-type triterpenoid isolated from Potentilla anserina L. Rosamultin has inhibitory effects against HIV-1 protease[1]. Rosamultin has the potential for treating H2O2-induced oxidative stress injury through its antioxidant and antiapoptosis effects[2].

Name	Rosamultin
Synonyms	Tormentic acid glucosyl Rosamutin ursolazuroside 1

Description	Rosamultin is a 19 α-hydroxyursane-type triterpenoid isolated from Potentilla anserina L. Rosamultin has inhibitory effects against HIV-1 protease[1]. Rosamultin has the potential for treating H2O2-induced oxidative stress injury through its antioxidant and antiapoptosis effects[2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Metabolic Enzyme/Protease >> HIV Protease
Target	IC50: HIV-1 protease[1]
In Vitro	Rosamultin isolated from the root of R. rugosa inhibits HIV-1 protease by 53% at a concentration of 100 μM[1].
References	[1]. Zhang L, et al. Protective Effect of Rosamultin against H2O2-Induced Oxidative Stress and Apoptosis in H9c2 Cardiomyocytes.Oxid Med Cell Longev. 2018 Jul 16;2018:8415610. [2]. Park JC, et al. Anti-HIV protease activity from rosa family plant extracts and rosamultin from Rosa rugosa.J Med Food. 2005 Spring;8(1):107-9.