Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Azathramycin
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Purity: 98.0%
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Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Azathramycin
Price: ￥726.0/10mg ￥1876.0/250mg ￥1206.0/100mg ￥916.0/50mg
Purity: 97.0%
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ShangHai DC Chemicals Co.,Ltd
China
Product Name: Azathramycin
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DC Chemicals Limited
China
Product Name: Azathramycin
Price: $100.0/100mg $200.0/250mg $400.0/1g
Purity: 98.0%
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: DESMETHYLAZYTHROMICIN
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Purity: 98.0%
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76801-85-9

76801-85-9 structure

Name: Azathramycin
Chemical Name: (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,8,10,12,14-hexamethyl-1-oxa-6-azacyclopentadecan-15-one
CAS Number: 76801-85-9
Molecular Formula: C₃₇H₇₀N₂O₁₂
Molecular Weight: 734.958
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2018-07-26 16:29:36
Modify Date: 2024-01-02 09:47:35
Azathramycin is an antibiotic.

Name	(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,8,10,12,14-hexamethyl-1-oxa-6-azacyclopentadecan-15-one
Synonyms	9-deokso-9a-aza-9a-homoeritromicin A Desmethylazithromycin 1-oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)- 9a-N-desmethyl azithromycin (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-Ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-15-oxo-11-{[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy}-1-oxa-6-azacyclopentadecan-13-yl 2, 6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranoside DD-Azaerythromycin A 10-Dihydro-10-deoxo-11-azaerythromycin A 9-Deoxo-9a-aza-9a-homo Erythromycin A(Desmethyl Azithromycin) (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-Ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-15-oxo-11-{[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy}-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranoside 9-deoxo-9-dihydro-9a-aza-9a-homoerythromycin A 9a-aza-9-deoxo-9a-homoerythromycin A 9-deoxo-9a-aza-9a-homoerythromycin Azaerythromycin A UNII-4LSP9FJT5B 1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β -D-xylo-hexopyranosyl]oxy]-, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)- 9-deoxo-9a-aza-9a-homoerythromycin A Azathramycin

Description	Azathramycin is an antibiotic.
Related Catalog	Signaling Pathways >> Autophagy >> Autophagy Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection
References	[1]. Noedl H, Krudsood S, Leowattana W, In vitro antimalarial activity of azithromycin, artesunate, and quinine in combination and correlation with clinical outcome. Antimicrob Agents Chemother. 2007 Feb;51(2):651-6. [2]. Hiwatashi Y, Maeda M, Fukushima H, Azithromycin suppresses proliferation, interleukin production and mitogen-activated protein kinases in human peripheral-blood mononuclear cells stimulated with bacterial superantigen. J Pharm Pharmacol. 2011 Oct;63(10):1320-6. [3]. Fernandez-Obregon AC. Azithromycin for the treatment of acne. Int J Dermatol. 2000 Jan;39(1):45-50.

Density	1.2±0.1 g/cm3
Boiling Point	815.2±65.0 °C at 760 mmHg
Melting Point	126-136ºC
Molecular Formula	C₃₇H₇₀N₂O₁₂
Molecular Weight	734.958
Flash Point	446.8±34.3 °C
Exact Mass	734.492859
PSA	188.87000
LogP	3.11
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.536
Storage condition	-20℃

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H319
Precautionary Statements	P305 + P351 + P338
RIDADR	NONH for all modes of transport

342371-84-0

~83%

76801-85-9

Literature: ALEMBIC LIMITED Patent: WO2009/156938 A2, 2009 ; Location in patent: Page/Page column 8 ;

944124-75-8

76801-85-9

Literature: WO2007/80507 A2, ; Page/Page column 11 ;

111321-02-9

~44%

76801-85-9

Literature: Costa, Anna M.; Vilarrasa, Jaume Tetrahedron Letters, 2000 , vol. 41, # 18 p. 3371 - 3375

227948-37-0

76801-85-9

Literature: Lee, Younjoo; Choi, Jun Yong; Fu, Hong; Harvey, Colin; Ravindran, Sandeep; Roush, William R.; Boothroyd, John C.; Khosla, Chaitan Journal of Medicinal Chemistry, 2011 , vol. 54, # 8 p. 2792 - 2804

114-07-8

76801-85-9

Literature: Journal of Medicinal Chemistry, , vol. 54, # 8 p. 2792 - 2804

Precursor 3
342371-84-0 111321-02-9 114-07-8
DownStream 1
83905-01-5

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