Shanghai Nianxing Industrial Co., Ltd
China
Product Name: LY210073?
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Purity: 98.0%
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: (E)-7-Carboxy-3-((6-(4-methoxyphenyl)-5-hexenyl)oxy)-9-oxo-9H-xanthene-4-propanoic acid
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Purity: 98.0%
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148291-65-0

148291-65-0 structure

148291-65-0 structure

Name: LY210073
Chemical Name: 5-(2-carboxyethyl)-6-[6-(4-methoxyphenyl)hex-5-enoxy]-9-oxoxanthene-2-carboxylic acid
CAS Number: 148291-65-0
Molecular Formula: C₃₀H₂₈O₈
Molecular Weight: 516.53900
Catalog: Signaling Pathways GPCR/G Protein Leukotriene Receptor
Create Date: 2016-11-27 22:19:26
Modify Date: 2024-01-31 17:08:35
LY210073 is a Leukotriene B4 (LTB4) receptor antagonist with an IC50 of 6.2 nM.

Name	5-(2-carboxyethyl)-6-[6-(4-methoxyphenyl)hex-5-enoxy]-9-oxoxanthene-2-carboxylic acid
Synonyms	LY210073

Description	LY210073 is a Leukotriene B4 (LTB4) receptor antagonist with an IC50 of 6.2 nM.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Leukotriene Receptor Research Areas >> Inflammation/Immunology
Target	LTB4:6.2 nM (IC50)
In Vitro	LY210073 is a Leukotriene B4 (LTB4) receptor antagonist with an IC50 of 6.2±0.1 nM. LY2100731 (Compound 32) appears to be one of the strongest inhibitors of LTB4 receptor binding reported so far[1].
References	[1]. Jackson WT, et al. Design, synthesis, and pharmacological evaluation of potent xanthone dicarboxylic acid leukotriene B4 receptor antagonists. J Med Chem. 1993 Jun 11;36(12):1726-34.

Density	1.314g/cm3
Boiling Point	775.7ºC at 760mmHg
Molecular Formula	C₃₀H₂₈O₈
Molecular Weight	516.53900
Flash Point	257.2ºC
Exact Mass	516.17800
PSA	123.27000
LogP	5.93270
Vapour Pressure	2.52E-25mmHg at 25°C
Index of Refraction	1.636
Storage condition	2-8℃

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