2104-66-7
2104-66-7 structure
- Name: 2-amino-9-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-methylsulfanyl-3H-purin-6-one
- Chemical Name: 4-(4-chloroanilino)-4-oxobutanoic acid
- CAS Number: 2104-66-7
- Molecular Formula: C11H15N5O5S
- Molecular Weight: 329.33
- Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
- Create Date: 2016-12-31 23:32:30
- Modify Date: 2025-08-26 15:53:29
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8-(Methylthio)guanosine is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].
| Name | 4-(4-chloroanilino)-4-oxobutanoic acid |
|---|---|
| Synonyms |
8-methylsulfanyl-guanosine
8-Methylmercapto-guanosin 8-Methylthioguanosin 8-methylthioguanosine |
| Description | 8-(Methylthio)guanosine is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1]. |
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| Related Catalog | |
| References |
| Density | 2.12g/cm3 |
|---|---|
| Boiling Point | 757.3ºC at 760 mmHg |
| Molecular Formula | C11H15N5O5S |
| Molecular Weight | 329.33 |
| Flash Point | 411.8ºC |
| Exact Mass | 329.07900 |
| PSA | 184.81000 |
| Vapour Pressure | 4.18E-24mmHg at 25°C |
| Index of Refraction | 1.915 |
|
~63%
2104-66-7 |
| Literature: Giorgi, Tatiana; Lena, Stefano; Mariani, Paolo; Cremonini, Mauro A.; Masiero, Stefano; Pieraccini, Silvia; Rabe, Juergen P.; Samori, Paolo; Spada, Gian Piero; Gottarelli, Giovanni Journal of the American Chemical Society, 2003 , vol. 125, # 48 p. 14741 - 14749 |
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~%
2104-66-7 |
| Literature: Lin; Cheng; Ishiguro; Sartorelli Journal of Medicinal Chemistry, 1985 , vol. 28, # 9 p. 1194 - 1198 |
| Precursor 3 | |
|---|---|
| DownStream 0 | |