Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Pyrrolidine,1,1'-(2-butyne-1,4-diyl)bis-
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

51-73-0

51-73-0 structure

Name: Pyrrolidine,1,1'-(2-butyne-1,4-diyl)bis-
Chemical Name: 1-(4-pyrrolidin-1-ylbut-2-ynyl)pyrrolidine
CAS Number: 51-73-0
Molecular Formula: C₁₂H₂₀N₂
Molecular Weight: 192.30100
Create Date: 2017-04-07 23:03:48
Modify Date: 2025-09-09 02:51:30

Name	1-(4-pyrrolidin-1-ylbut-2-ynyl)pyrrolidine
Synonyms	Tremorin 1,4-Dipyrrolidine-2-butyne Tremorine 1,1'-but-2-yne-1,4-diyl-bis-pyrrolidine 1,4-dipyrrolidino-but-2-yne 1,4-Dipyrrolidino-2-butyne Biofermin 1,4-Dipyrrolidino-but-2-in 1,4-Dipyrrolidino-2-butin 1,4-Dipyrrolidinyl-2-butyne

Density	1.014g/cm3
Boiling Point	285.6ºC at 760mmHg
Molecular Formula	C₁₂H₂₀N₂
Molecular Weight	192.30100
Flash Point	118.4ºC
Exact Mass	192.16300
PSA	6.48000
LogP	1.05720
Index of Refraction	1.531

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UY0175000

CHEMICAL NAME :: Pyrrolidine, 1,1'-(2-butynylene)di-

CAS REGISTRY NUMBER :: 51-73-0

BEILSTEIN REFERENCE NO. :: 0006119

LAST UPDATED :: 199612

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C12-H20-N2

MOLECULAR WEIGHT :: 192.34

WISWESSER LINE NOTATION :: T5NTJ A2UU2- AT5NTJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 25 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - ataxia

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 21,1727,1971

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 58 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - body temperature decrease

REFERENCE :: NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 56(3),83S,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 112 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#12070

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: 5 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Gastrointestinal - changes in structure or function of salivary glands Gastrointestinal - hypermotility, diarrhea

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 135,447,1962

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - wild bird species

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 21,315,1972

RIDADR	UN 2810
Packaging Group	III
Hazard Class	6.1(b)
HS Code	2933990090

123-75-1

50-00-0

74-86-2

51-73-0

Literature: Fegley et al. Journal of the American Chemical Society, 1957 , vol. 79, p. 4144

123-75-1

821-10-3

51-73-0

Literature: Biel; Di Pierro Journal of the American Chemical Society, 1958 , vol. 80, p. 4609,4611 Full Text Show Details Reppe et al. Justus Liebigs Annalen der Chemie, 1955 , vol. 596, p. 65

Precursor 4
123-75-1 50-00-0 74-86-2 821-10-3
DownStream 0

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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