125700-35-8

125700-35-8 structure
125700-35-8 structure
  • Name: fmoc-[15n]val-oh
  • Chemical Name: N-(9-Fluorenylmethoxycarbonyl)-L-valine-15N
  • CAS Number: 125700-35-8
  • Molecular Formula: C20H2115NO4
  • Molecular Weight: 340.38
  • Catalog: Biochemical Amino acids and their derivatives Proline derivatives
  • Create Date: 2018-04-01 08:00:00
  • Modify Date: 2024-01-10 16:28:02
  • Fmoc-L-Val-OH-15N is a 15N-labeled Leucomalachite green. Leucomalachite green is a triphenylmethane dye used to detect blood. Leucomalachite green, a major metabolite of malachite green, is a potential carcinogen, teratogen and mutagen[1][2].

Name N-(9-Fluorenylmethoxycarbonyl)-L-valine-15N
Synonyms MFCD00190536
L-Valine-15N,N-Fmoc derivative
Fmoc-Val-OH-15N
Description Fmoc-L-Val-OH-15N is a 15N-labeled Leucomalachite green. Leucomalachite green is a triphenylmethane dye used to detect blood. Leucomalachite green, a major metabolite of malachite green, is a potential carcinogen, teratogen and mutagen[1][2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-236.

[2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-236.

Melting Point 143-145ºC
Molecular Formula C20H2115NO4
Molecular Weight 340.38
Exact Mass 340.14400
PSA 75.63000
LogP 4.02520
Storage condition -15°C
RIDADR NONH for all modes of transport
WGK Germany 3