fmoc-[15n]val-oh

Modify Date: 2024-01-10 16:28:02

fmoc-[15n]val-oh Structure
fmoc-[15n]val-oh structure
Common Name fmoc-[15n]val-oh
CAS Number 125700-35-8 Molecular Weight 340.38
Density N/A Boiling Point N/A
Molecular Formula C20H2115NO4 Melting Point 143-145ºC
MSDS Chinese USA Flash Point N/A

 Use of fmoc-[15n]val-oh


Fmoc-L-Val-OH-15N is a 15N-labeled Leucomalachite green. Leucomalachite green is a triphenylmethane dye used to detect blood. Leucomalachite green, a major metabolite of malachite green, is a potential carcinogen, teratogen and mutagen[1][2].

 Names

Name N-(9-Fluorenylmethoxycarbonyl)-L-valine-15N
Synonym More Synonyms

 fmoc-[15n]val-oh Biological Activity

Description Fmoc-L-Val-OH-15N is a 15N-labeled Leucomalachite green. Leucomalachite green is a triphenylmethane dye used to detect blood. Leucomalachite green, a major metabolite of malachite green, is a potential carcinogen, teratogen and mutagen[1][2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-236.

[2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-236.

 Chemical & Physical Properties

Melting Point 143-145ºC
Molecular Formula C20H2115NO4
Molecular Weight 340.38
Exact Mass 340.14400
PSA 75.63000
LogP 4.02520
Storage condition -15°C

 Safety Information

RIDADR NONH for all modes of transport
WGK Germany 3

 Synonyms

MFCD00190536
L-Valine-15N,N-Fmoc derivative
Fmoc-Val-OH-15N