1269815-17-9
1269815-17-9 structure
- Name: CDK-IN-2
- Chemical Name: (3R)-N-[5-chloro-4-(5-fluoro-2-methoxyphenyl)pyridin-2-yl]piperidine-3-carboxamide
- CAS Number: 1269815-17-9
- Molecular Formula: C18H19ClFN3O2
- Molecular Weight: 363.81400
- Catalog: Research Areas Cancer
- Create Date: 2016-03-23 16:01:04
- Modify Date: 2024-02-10 22:59:45
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CDK-IN-2 is a potent and specific CDK9 inhibitor with IC50 of <8 nM, extracted from reference 1, example 4.IC50 Value: <8 nM [1]Target: CDK9In vitro:In vivo:
| Name | (3R)-N-[5-chloro-4-(5-fluoro-2-methoxyphenyl)pyridin-2-yl]piperidine-3-carboxamide |
|---|---|
| Synonyms |
(R)-piperidine-3-carboxylic acid [5-chloro-4-(5-fluoro-2-methoxyphenyl)-pyridin-2-yl]-amide
(R)-N-(5-chloro-4-(5-fluoro-2-methoxyphenyl)pyridin-2-yl)piperidine-3-carboxamide trifluoroacetate CDK inhibitor II| CDK-IN-2 |
| Description | CDK-IN-2 is a potent and specific CDK9 inhibitor with IC50 of <8 nM, extracted from reference 1, example 4.IC50 Value: <8 nM [1]Target: CDK9In vitro:In vivo: |
|---|---|
| Related Catalog | |
| Target |
CDK9/cyclinT1:8 nM (IC50) |
| References |
[1]. Keith B Pfister, et al. Heteroaryl compounds as kinase inhibitors. 2011, WO2011026917A1. |
| Molecular Formula | C18H19ClFN3O2 |
|---|---|
| Molecular Weight | 363.81400 |
| Exact Mass | 363.11500 |
| PSA | 66.74000 |
| LogP | 4.46610 |
| Storage condition | 2-8℃ |