37905-08-1

37905-08-1 structure

Name: Jolkinolide B
Chemical Name: 1,4-dibutyl-N-(2,6-dimethylphenyl)piperazine-2-carboxamide,nitrous acid
CAS Number: 37905-08-1
Molecular Formula: C₂₀H₂₆O₄
Molecular Weight: 330.418
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2018-02-16 08:00:00
Modify Date: 2024-01-06 11:38:14
Jolkinolide B, a bioactive diterpene isolated from the roots of Euphorbia fischeriana Steud, is known to induce apoptosis in cancer cells[1].

Name	1,4-dibutyl-N-(2,6-dimethylphenyl)piperazine-2-carboxamide,nitrous acid
Synonyms	(4aR,6aS,7aR,10aR,11aR,11bR,11cR)-4,4,8,11c-Tetramethyl-1,2,3,4,4a,5,6,11a,11b,11c-decahydrobisoxireno[3,4:1,10a]phenanthro[3,2-b]furan-9(7aH)-one 2-Piperazinecarboxamide,1,4-dibutyl-N-(2,6-dimethylphenyl)-,dinitrate 1,4-dibutyl-n-(2,6-dimethylphenyl)piperazine-2-carboxamide ntrite(1:2) jokiolide B jolkinolide B Bisoxireno[3,4:1,10a]phenanthro[3,2-b]furan-9(7aH)-one, 1,2,3,4,4a,5,6,11a,11b,11c-decahydro-4,4,8,11c-tetramethyl-, (4aR,6aS,7aR,10aR,11aR,11bR,11cR)- 2-Piperazinecarboxanilide,1,4-dibutyl-2',6'-dimethyl-,dinitrate 1,4-dibutyl-N-(2,6-dimethylphenyl)piperazine-2-carboxamide

Description	Jolkinolide B, a bioactive diterpene isolated from the roots of Euphorbia fischeriana Steud, is known to induce apoptosis in cancer cells[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
Target	IC50: apoptosis[1]
References	[1]. Wang, J., Zhou, Y., Bai, X. et al. Jolkinolide B from Euphorbia fischeriana Steud induces apoptosis in human leukemic U937 cells through PI3K/Akt and XIAP pathways. Mol Cells 32, 451–457 (2011).