115044-75-2

115044-75-2 structure
115044-75-2 structure
  • Name: 2-chloro-3'-deoxyadenosine
  • Chemical Name: (2R,3R,5S)-2-(6-amino-2-chloropurin-9-yl)-5-(hydroxymethyl)oxolan-3-ol
  • CAS Number: 115044-75-2
  • Molecular Formula: C10H12ClN5O3
  • Molecular Weight: 285.69
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
  • Create Date: 2017-10-18 12:19:49
  • Modify Date: 2024-01-09 16:37:43
  • 2-Chloro-3′-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name (2R,3R,5S)-2-(6-amino-2-chloropurin-9-yl)-5-(hydroxymethyl)oxolan-3-ol
Synonyms biodribin
C10H14ClN5O3
Adenosine,2-chloro-3'-deoxy
2-Chloro-3'-deoxyadenosine
2-chlorocordycepin
3'-Deoxy-2-chloroadenosine
UNII-JYW18Y92UP
Description 2-Chloro-3′-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Density 2.03g/cm3
Boiling Point 547.6ºC at 760mmHg
Molecular Formula C10H12ClN5O3
Molecular Weight 285.69
Flash Point 285ºC
Exact Mass 285.06300
PSA 119.31000
LogP 0.28380
Vapour Pressure 7.95E-13mmHg at 25°C
Index of Refraction 1.87