204451-50-3
204451-50-3 structure
- Name: L-Lysine-15N dihydrochloride
- Chemical Name: (2S)-6-amino-2-azanylhexanoic acid
- CAS Number: 204451-50-3
- Molecular Formula: C6H16Cl2N15NO2
- Molecular Weight: 220.10
- Catalog: Research Areas Cancer
- Create Date: 2017-05-28 22:40:06
- Modify Date: 2024-01-10 14:24:10
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L-Lysine-15N (dihydrochloride) is a 15N-labeled Deruxtecan. Deruxtecan is an ADC drug-linker conjugate composed of a derivative of DX-8951 (DXd) and amaleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.
| Name | (2S)-6-amino-2-azanylhexanoic acid |
|---|---|
| Synonyms | L-Lysine-2-15N dihydrochloride |
| Description | L-Lysine-15N (dihydrochloride) is a 15N-labeled Deruxtecan. Deruxtecan is an ADC drug-linker conjugate composed of a derivative of DX-8951 (DXd) and amaleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402. |
|---|---|
| Related Catalog | |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75]. |
| References |
| Melting Point | 200-206ºC (dec.)(lit.) |
|---|---|
| Molecular Formula | C6H16Cl2N15NO2 |
| Molecular Weight | 220.10 |
| Exact Mass | 219.05600 |
| PSA | 89.34000 |
| LogP | 2.53190 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Safety Phrases | 22-24/25 |
| RIDADR | NONH for all modes of transport |