103613-84-9

103613-84-9 structure
103613-84-9 structure
  • Name: (N-Me-Tyr1,N-Me-Arg7,D-Leu-NHEt8)-Dynorphin A (1-8) trifluoroacetate salt
  • Chemical Name: (2R)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-3-(4-hydroxyphenyl)-2-(methylamino)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]pentanoyl]-met
  • CAS Number: 103613-84-9
  • Molecular Formula: C50H81N15O9
  • Molecular Weight: 1036.273
  • Catalog: Signaling Pathways GPCR/G Protein Opioid Receptor
  • Create Date: 2017-04-27 07:32:21
  • Modify Date: 2024-01-03 10:46:50
  • (N-Me-Tyr1,N-Me-Arg7,D-Leu-NHEt8)-Dynorphin A (1-8) (E-2078), a stable Dynorphin A (1–8) (HY-P2159) analog, is a kappa opioid receptor (KOR) agonist[1].

Name (2R)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-3-(4-hydroxyphenyl)-2-(methylamino)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]pentanoyl]-met
Synonyms H-MeTyr-Gly-Gly-Phe-Leu-Arg-MeArg-D-Leu-NHEt
D-Leucinamide, N-methyl-L-tyrosylglycylglycyl-L-phenylalanyl-L-leucyl-N-(diaminomethylene)-L-ornithyl-N-(diaminomethylene)-N-methyl-L-ornithyl-N-ethyl-
N-Methyl-L-tyrosylglycylglycyl-L-phenylalanyl-L-leucyl-N-(diaminomethylene)-L-ornithyl-N-(diaminomethylene)-N-methyl-L-ornithyl-N-ethyl-D-leucinamide
N-Me-Tyr-gly-gly-phe-leu-arg-N-Me-arg-leu-NH-C2H5
N-Methyltyrosyl-glycyl-glycyl-phenylalanyl-leucyl-arginyl-N-methyl-arginyl-leucyl ethylamide
E-2078
D-Leucinamide,N-methyl-L-tyrosylglycylglycyl-L-phenylalanyl-L-leucyl-L-arginyl-N2-methyl-L-arginyl-N-ethyl
C50H81N15O9
MeTyr-Gly-Gly-Phe-Leu-Arg-MeArg-D-Leu-NHEt
Description (N-Me-Tyr1,N-Me-Arg7,D-Leu-NHEt8)-Dynorphin A (1-8) (E-2078), a stable Dynorphin A (1–8) (HY-P2159) analog, is a kappa opioid receptor (KOR) agonist[1].
Related Catalog
Target

κ Opioid Receptor/KOR

References

[1]. Butelman ER, et al. Effects of E-2078, a stable dynorphin A(1-8) analog, on sedation and serum prolactin levels in rhesus monkeys. Psychopharmacology (Berl). 1999 Nov;147(1):73-80.  

Density 1.3±0.1 g/cm3
Molecular Formula C50H81N15O9
Molecular Weight 1036.273
Exact Mass 1035.634155
PSA 404.50000
LogP 1.86
Index of Refraction 1.616