130727-42-3
130727-42-3 structure
- Name: Thiol-C9-PEG5
- Chemical Name: 2-[2-[2-[2-(11-sulfanylundecoxy)ethoxy]ethoxy]ethoxy]ethanol
- CAS Number: 130727-42-3
- Molecular Formula: C19H40O5S
- Molecular Weight: 380.58300
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2016-12-01 04:16:00
- Modify Date: 2025-08-26 17:24:08
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Thiol-C9-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 2-[2-[2-[2-(11-sulfanylundecoxy)ethoxy]ethoxy]ethoxy]ethanol |
|---|---|
| Synonyms |
3,6,9,12-Tetraoxatricosan-1-ol,23-mercapto
23-mercapto-3,6,9,12-tetraoxatricosan-1-ol MUTEG |
| Description | Thiol-C9-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Molecular Formula | C19H40O5S |
|---|---|
| Molecular Weight | 380.58300 |
| Exact Mass | 380.26000 |
| PSA | 95.95000 |
| LogP | 3.48580 |
|
~99%
130727-42-3 |
| Literature: Chou, Stanley S.; De, Mrinmoy; Kim, Jaemyung; Byun, Segi; Dykstra, Conner; Yu, Jin; Huang, Jiaxing; Dravid, Vinayak P. Journal of the American Chemical Society, 2013 , vol. 135, # 12 p. 4584 - 4587 |
|
~%
130727-42-3 |
| Literature: Choi, Inseong; Kim, Young-Kwan; Min, Dal-Hee; Lee, Sangwook; Yeo, Woon-Seok Journal of the American Chemical Society, 2011 , vol. 133, # 42 p. 16718 - 16721 |
|
~%
130727-42-3 |
| Literature: Choi, Inseong; Kim, Young-Kwan; Min, Dal-Hee; Lee, Sangwook; Yeo, Woon-Seok Journal of the American Chemical Society, 2011 , vol. 133, # 42 p. 16718 - 16721 |
|
~%
130727-42-3 |
| Literature: Pale-Grosdemange, Catherine; Simon, Ethan S.; Prime, Kevin L.; Whitesides, George M. Journal of the American Chemical Society, 1991 , vol. 113, # 1 p. 12 - 20 |
|
~%
130727-42-3 |
| Literature: Pale-Grosdemange, Catherine; Simon, Ethan S.; Prime, Kevin L.; Whitesides, George M. Journal of the American Chemical Society, 1991 , vol. 113, # 1 p. 12 - 20 |
|
~%
130727-42-3 |
| Literature: Choi, Inseong; Kim, Young-Kwan; Min, Dal-Hee; Lee, Sangwook; Yeo, Woon-Seok Journal of the American Chemical Society, 2011 , vol. 133, # 42 p. 16718 - 16721 |
|
~%
130727-42-3 |
| Literature: Chou, Stanley S.; De, Mrinmoy; Kim, Jaemyung; Byun, Segi; Dykstra, Conner; Yu, Jin; Huang, Jiaxing; Dravid, Vinayak P. Journal of the American Chemical Society, 2013 , vol. 135, # 12 p. 4584 - 4587 |
|
~%
130727-42-3 |
| Literature: Chou, Stanley S.; De, Mrinmoy; Kim, Jaemyung; Byun, Segi; Dykstra, Conner; Yu, Jin; Huang, Jiaxing; Dravid, Vinayak P. Journal of the American Chemical Society, 2013 , vol. 135, # 12 p. 4584 - 4587 |
| Precursor 8 | |
|---|---|
| DownStream 0 | |