Thiol-C9-PEG5
Modify Date: 2024-01-29 16:35:09
Thiol-C9-PEG5 structure
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Common Name | Thiol-C9-PEG5 | ||
|---|---|---|---|---|
| CAS Number | 130727-42-3 | Molecular Weight | 380.58300 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H40O5S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Thiol-C9-PEG5Thiol-C9-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
| Name | 2-[2-[2-[2-(11-sulfanylundecoxy)ethoxy]ethoxy]ethoxy]ethanol |
|---|---|
| Synonym | More Synonyms |
| Description | Thiol-C9-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Molecular Formula | C19H40O5S |
|---|---|
| Molecular Weight | 380.58300 |
| Exact Mass | 380.26000 |
| PSA | 95.95000 |
| LogP | 3.48580 |
|
~99%
Thiol-C9-PEG5 CAS#:130727-42-3 |
| Literature: Chou, Stanley S.; De, Mrinmoy; Kim, Jaemyung; Byun, Segi; Dykstra, Conner; Yu, Jin; Huang, Jiaxing; Dravid, Vinayak P. Journal of the American Chemical Society, 2013 , vol. 135, # 12 p. 4584 - 4587 |
|
~%
Thiol-C9-PEG5 CAS#:130727-42-3 |
| Literature: Choi, Inseong; Kim, Young-Kwan; Min, Dal-Hee; Lee, Sangwook; Yeo, Woon-Seok Journal of the American Chemical Society, 2011 , vol. 133, # 42 p. 16718 - 16721 |
|
~%
Thiol-C9-PEG5 CAS#:130727-42-3 |
| Literature: Choi, Inseong; Kim, Young-Kwan; Min, Dal-Hee; Lee, Sangwook; Yeo, Woon-Seok Journal of the American Chemical Society, 2011 , vol. 133, # 42 p. 16718 - 16721 |
|
~%
Thiol-C9-PEG5 CAS#:130727-42-3 |
| Literature: Pale-Grosdemange, Catherine; Simon, Ethan S.; Prime, Kevin L.; Whitesides, George M. Journal of the American Chemical Society, 1991 , vol. 113, # 1 p. 12 - 20 |
|
~%
Thiol-C9-PEG5 CAS#:130727-42-3 |
| Literature: Pale-Grosdemange, Catherine; Simon, Ethan S.; Prime, Kevin L.; Whitesides, George M. Journal of the American Chemical Society, 1991 , vol. 113, # 1 p. 12 - 20 |
|
~%
Thiol-C9-PEG5 CAS#:130727-42-3 |
| Literature: Choi, Inseong; Kim, Young-Kwan; Min, Dal-Hee; Lee, Sangwook; Yeo, Woon-Seok Journal of the American Chemical Society, 2011 , vol. 133, # 42 p. 16718 - 16721 |
|
~%
Thiol-C9-PEG5 CAS#:130727-42-3 |
| Literature: Chou, Stanley S.; De, Mrinmoy; Kim, Jaemyung; Byun, Segi; Dykstra, Conner; Yu, Jin; Huang, Jiaxing; Dravid, Vinayak P. Journal of the American Chemical Society, 2013 , vol. 135, # 12 p. 4584 - 4587 |
|
~%
Thiol-C9-PEG5 CAS#:130727-42-3 |
| Literature: Chou, Stanley S.; De, Mrinmoy; Kim, Jaemyung; Byun, Segi; Dykstra, Conner; Yu, Jin; Huang, Jiaxing; Dravid, Vinayak P. Journal of the American Chemical Society, 2013 , vol. 135, # 12 p. 4584 - 4587 |
![S-[11-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]undecyl] ethanethioate structure](https://www.chemsrc.com/caspic/074/130727-51-4.png)
![2-[2-[2-(2-undec-10-enoxyethoxy)ethoxy]ethoxy]ethanol structure](https://www.chemsrc.com/caspic/091/130727-46-7.png)
| Precursor 8 | |
|---|---|
| DownStream 0 | |
| 3,6,9,12-Tetraoxatricosan-1-ol,23-mercapto |
| 23-mercapto-3,6,9,12-tetraoxatricosan-1-ol |
| MUTEG |