141835-49-6

141835-49-6 structure

Name: RG 14893
Chemical Name: 4-[2-[methyl(2-phenylethyl)amino]-2-oxoethyl]-8-phenylmethoxynaphthalene-2-carboxylic acid
CAS Number: 141835-49-6
Molecular Formula: C₂₉H₂₇NO₄
Molecular Weight: 453.52900
Catalog: Signaling Pathways GPCR/G Protein Leukotriene Receptor
Create Date: 2016-08-13 23:17:22
Modify Date: 2024-04-06 16:48:52
RG 14893 is a high affinity, competitive, orally active leukotriene B4 receptor antagonist[1].

Name	4-[2-[methyl(2-phenylethyl)amino]-2-oxoethyl]-8-phenylmethoxynaphthalene-2-carboxylic acid

Description	RG 14893 is a high affinity, competitive, orally active leukotriene B4 receptor antagonist[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Leukotriene Receptor Research Areas >> Inflammation/Immunology
References	[1]. F C Huang, et al. 4-[2-[Methyl(2-phenethyl)amino]-2-oxoethyl]-8-(phenylmethoxy)-2- naphthalenecarboxylic acid: a high affinity, competitive, orally active leukotriene B4 receptor antagonist. J Med Chem 1992 Oct 30;35(22):4253-5.

Density	1.231g/cm3
Boiling Point	678.5ºC at 760mmHg
Molecular Formula	C₂₉H₂₇NO₄
Molecular Weight	453.52900
Flash Point	364.1ºC
Exact Mass	453.19400
PSA	66.84000
LogP	5.36060
Vapour Pressure	2.45E-19mmHg at 25°C
Index of Refraction	1.647

163685-19-6

~89%

141835-49-6

Literature: Chan, Wan K.; Huang, Fu-Chih; Morrissette, Matthew M.; Warus, James D.; Moriarty, Kevin J.; Galemmo, Robert A.; Dankulich, William D.; Poli, Gregory; Sutherland, Charles A. Journal of Medicinal Chemistry, 1996 , vol. 39, # 19 p. 3756 - 3768

Precursor 1
163685-19-6
DownStream 0

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