209860-87-7
209860-87-7 structure
- Name: Tafluprost
- Chemical Name: tafluprost
- CAS Number: 209860-87-7
- Molecular Formula: C25H34F2O5
- Molecular Weight: 452.531
- Catalog: API Hormone and endocrine-regulating drugs Prostaglandins
- Create Date: 2018-06-01 08:00:00
- Modify Date: 2026-07-03 12:11:38
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Tafluprost(AFP-168) is an anti-glaucoma prostaglandin (PG) analog.Target:OthersTafluprost showed significant IOP-lowering effects without any safety concerns in patients with various types of glaucoma and OH in daily clinical practice and tafluprost is highly effective in any therapeutic patterns [1]. Tafluprost with reduced BAK has potential as a superior antiglaucoma drug, not only for its IOP-lowering effect, but also for its good corneal safety profile [2]. Tafluprost single-use vials treatment was effective in reducing IOP over the 3 years of this study, but visual field performance worsened by 10.3%-13.8% in patients with normal-tension glaucoma. Safety was satisfactory [3].
| Name | tafluprost |
|---|---|
| Synonyms |
TafluprostQ: What is Tafluprost Q: What is the CAS Number of Tafluprost Q: What is the storage condition of Tafluprost Q: What e the applications of Tafluprost
(Z)Isopropyl 7-((1R,2R,3R,5S)-2-((E)-3,3-difluoro-4-phenoxy-but-1-en-1-yl)-3,5-dihydroxy-cyclopentyl)ht-5-enoat MK2452|||AFP-168 propan-2-yl (Z)-7-[(1R,2R,3R,5S)-2-[(E)-3,3-difluoro-4-phenoxybut-1-enyl]-3,5-dihydroxycyclopentyl]ht-5-enoate Tafluprost, 10 mM in DMSO He has fluprostaglandin UNII-1O6WQ6T7G3 Tapros TAFLUPROST TafL 209-7 Tafluprost propan-2-yl (Z)-7-[(1R,2R,3R,5S)-2-[(E)-3,3-difluoro-4-phenoxybut-1-enyl]-3,5-dihydroxycyclopentyl]hept-5-enoate Isopropyl (Z)-7-[(1R,2R,3R,5S)-2-[(E)-3,3-Difluoro-4-phenoxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-5-htenoate AFP-168 (Z)-Isopropyl 7-((1R,2R,3R,5S)-2-((E)-3,3-difluoro-4-phenoxybut-1-en-1-yl)-3,5-dihydroxycyclopentyl)ht-5-enoate propan-2-yl (5Z)-7-[(1R,2R,3R,5S)-2-[(1E)-3,3-difluoro-4-phenoxybut-1-en-1-yl]-3,5-dihydroxycyclopentyl]ht-5-enoate Zioptan MK2452 MK-2452 5-Htenoic acid, 7-[(1R,2R,3R,5S)-2-[(1E)-3,3-difluoro-4-phenoxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-, 1-methylethyl ester, (5Z) aflupros Tafluprost //BP Tafluprosttrade Tafluprost5-Htenoic acid, 7-[(1R,2R,3R,5S)-2-[(1E)-3,3-difluoro-4-phenoxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-,1-methylethyl ester, (5Z) Saflutan (5Z)-7-[(1R,2R,3R,5S)-2-[(1E)-3,3-Difluoro-4-phenoxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-5-htenoic acid 1-methylethyl ester 15,15-DIFLUORO-9ALPHA,11ALPHA-DIHYDROXY-16-PHENOXY-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID, ISOPROPYL ESTER Isopropyl (5Z)-7-{(1R,2R,3R,5S)-2-((1E)-3,3-difluoro-4-phenoxybut-1-enyl)-3,5-dihydroxycyclopentyl}hept-5-enoate Taflotan TAFLUPROST DRUG SUBSTANCE isopropyl (z)-7-((1r,2r,3r,5s)-2-((e)-3,3-difluoro-4-phenoxybut-1-en-1-yl)-3,5-dihydroxycyclopentyl)ht-5-enoate Isopropyl (5Z)-7-{(1R,2R,3R,5S)-2-[(1E)-3,3-difluoro-4-phenoxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl}-5-heptenoate uprost |
| Description | Tafluprost(AFP-168) is an anti-glaucoma prostaglandin (PG) analog.Target:OthersTafluprost showed significant IOP-lowering effects without any safety concerns in patients with various types of glaucoma and OH in daily clinical practice and tafluprost is highly effective in any therapeutic patterns [1]. Tafluprost with reduced BAK has potential as a superior antiglaucoma drug, not only for its IOP-lowering effect, but also for its good corneal safety profile [2]. Tafluprost single-use vials treatment was effective in reducing IOP over the 3 years of this study, but visual field performance worsened by 10.3%-13.8% in patients with normal-tension glaucoma. Safety was satisfactory [3]. |
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| Related Catalog | |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 552.9±50.0 °C at 760 mmHg |
| Molecular Formula | C25H34F2O5 |
| Molecular Weight | 452.531 |
| Flash Point | 288.2±30.1 °C |
| Exact Mass | 452.237427 |
| PSA | 75.99000 |
| LogP | 4.23 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
| Index of Refraction | 1.549 |
| Storage condition | -20℃ |