121058-82-0

121058-82-0 structure

Name: N4-Acetyl-5’-O-(4,4’-dimethoxytrityl)-2’-deoxycytidine
Chemical Name: 5'-O-(4,4'-Dimethoxytrityl)-N4-acetyl-2'-deoxycytidine
CAS Number: 121058-82-0
Molecular Formula: C₃₂H₃₃N₃O₇
Molecular Weight: 571.62
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-12-27 19:22:32
Modify Date: 2024-01-05 10:57:23
N4-Acetyl-5’-O-(4,4’-dimethoxytrityl)-2’-deoxycytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	5'-O-(4,4'-Dimethoxytrityl)-N4-acetyl-2'-deoxycytidine
Synonyms	dmt-nac-dc n-acetyl-5'-dmt deoxycytidine

Description	N4-Acetyl-5’-O-(4,4’-dimethoxytrityl)-2’-deoxycytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

40615-36-9

3768-18-1

~63%

121058-82-0

Literature: Reddy, M. P.; Farooqui, Firdous; Hanna, Naeem B. Tetrahedron Letters, 1995 , vol. 36, # 49 p. 8929 - 8932

40615-36-9

108-24-7

65-46-3

~72%

121058-82-0

Literature: Pitsch, Stefan; Weiss, Patrick A.; Jenny, Luzi; Stutz, Alfred; Wu, Xiaolin Helvetica Chimica Acta, 2001 , vol. 84, # 12 p. 3773 - 3795

65-46-3

121058-82-0

Literature: Tetrahedron Letters, , vol. 39, # 14 p. 1897 - 1900

51432-41-8

121058-82-0

Literature: Tetrahedron Letters, , vol. 30, # 1 p. 71 - 74