eucatropine

Modify Date: 2025-08-20 11:08:36

eucatropine Structure
eucatropine structure
Common Name eucatropine
CAS Number 100-91-4 Molecular Weight 291.38500
Density 1.11g/cm3 Boiling Point 388.7ºC at 760mmHg
Molecular Formula C17H25NO3 Melting Point N/A
MSDS N/A Flash Point 188.8ºC

 Use of eucatropine


Eucatropine is a potent muscarinic acetylcholine receptor (mAChR) inhibitor with an IC50 value of 0.583 μM. Eucatropine is an anticholinergic agent[1].

 Names

Name (1,2,2,6-tetramethylpiperidin-4-yl) 2-hydroxy-2-phenylacetate
Synonym More Synonyms

 eucatropine Biological Activity

Description Eucatropine is a potent muscarinic acetylcholine receptor (mAChR) inhibitor with an IC50 value of 0.583 μM. Eucatropine is an anticholinergic agent[1].
Related Catalog
In Vivo Eucatropine (0-200 mg/mL; ICV) 作为 mAChR 拮抗剂,可通过猫的中枢胆碱能感受点产生行为效应[2]。
References

[1]. Schmeller T, et, al. Binding of tropane alkaloids to nicotinic and muscarinic acetylcholine receptors. Pharmazie. 1995 Jul;50(7):493-5.  

[2]. Beleslin DB, et, al. Comparative behavioral effects of anticholinergic agents in cats: psychomotor stimulation and aggression. Pharmacol Biochem Behav. 1986 Mar;24(3):581-6.  

 Chemical & Physical Properties

Density 1.11g/cm3
Boiling Point 388.7ºC at 760mmHg
Molecular Formula C17H25NO3
Molecular Weight 291.38500
Flash Point 188.8ºC
Exact Mass 291.18300
PSA 49.77000
LogP 2.46240
Vapour Pressure 9.97E-08mmHg at 25°C
InChIKey QSAVEGSLJISCDF-UHFFFAOYSA-N
SMILES CC1CC(OC(=O)C(O)c2ccccc2)CC(C)(C)N1C

 Precursor & DownStream

Precursor  1

DownStream  0

 eucatropineBioassay

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Name: Half life in mouse plasma
Source: ChEMBL
Target: N/A
External Id: CHEMBL4423497
Name: Half life in human plasma
Source: ChEMBL
Target: N/A
External Id: CHEMBL4423498
Name: Metabolic stability in human plasma assessed as parent compound remaining at 3 uM aft...
Source: ChEMBL
Target: N/A
External Id: CHEMBL4384251
Name: Metabolic stability in CD-1 mouse plasma assessed as parent compound remaining at 3 u...
Source: ChEMBL
Target: N/A
External Id: CHEMBL4384252
Name: Screen for inhibitors of RMI FANCM (MM2) intereaction
Source: 11908
Target: N/A
External Id: RMI-FANCM-MM2
Name: Plasma stability in CD-1 mouse assessed as compound remaining measured after 2 hrs
Source: ChEMBL
Target: N/A
External Id: CHEMBL5231947
Name: Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VER...
Source: ChEMBL
Target: Severe acute respiratory syndrome coronavirus 2
External Id: CHEMBL4513082
Name: Plasma stability in human assessed as compound remaining measured after 2 hrs
Source: ChEMBL
Target: N/A
External Id: CHEMBL5231946
Name: Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of Cac...
Source: ChEMBL
Target: Severe acute respiratory syndrome coronavirus 2
External Id: CHEMBL4303805
Name: Vibrio cholerae assay for pro-quorum sensing small molecules
Source: Southern Research Specialized Biocontainment Screening Center
Target: cyclic AMP receptor protein [Vibrio cholerae O1 biovar El Tor str. N16961]
External Id: Vcholera_QS_Pilot
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 Synonyms

Eucatropina
eucatropine
n-methyl-b-vinyldiacetonaikamine mandelate
Eucatropinum
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