BMS-593214

Modify Date: 2024-03-03 13:51:33

BMS-593214 Structure
BMS-593214 structure
Common Name BMS-593214
CAS Number 1004551-40-9 Molecular Weight 505.56400
Density N/A Boiling Point N/A
Molecular Formula C31H27N3O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BMS-593214


BMS-593214 is an active site-directed factor (F) VIIa inhibitor. BMS-593214 shows antithrombotic and antihaemostatic properties. BMS-593214 is a direct competitive inhibitor of human FVIIa and a non-competitive inhibitor of Viia-activated substrate FX. BMS-593214 prevents electroinduced carotid artery thrombosis (AT) and wire induced vena cava thrombosis (VT)[1].

 Names

Name 4-[2-[(6R,6aR,11bR)-2-carbamimidoyl-6,6a,7,11b-tetrahydro-5H-indeno[2,1-c]quinolin-6-yl]-5-hydroxy-4-methoxyphenyl]benzoic acid
Synonym More Synonyms

 BMS-593214 Biological Activity

Description BMS-593214 is an active site-directed factor (F) VIIa inhibitor. BMS-593214 shows antithrombotic and antihaemostatic properties. BMS-593214 is a direct competitive inhibitor of human FVIIa and a non-competitive inhibitor of Viia-activated substrate FX. BMS-593214 prevents electroinduced carotid artery thrombosis (AT) and wire induced vena cava thrombosis (VT)[1].
Related Catalog
References

[1]. Wong PC, et al. BMS-593214, an active site-directed factor VIIa inhibitor: enzyme kinetics, antithrombotic and antihaemostatic studies. Thromb Haemost. 2010 Aug;104(2):261-9.  

 Chemical & Physical Properties

Molecular Formula C31H27N3O4
Molecular Weight 505.56400
Exact Mass 505.20000
PSA 128.66000
LogP 6.45910

 Synonyms

unii-xd269g3o31
1ge
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