ethyl 6-fluoro-1-(4-fluorophenyl)-7-(3-methylpiperazin-1-yl)-4-oxo-1,8-naphthyridine-3-carboxylate

Modify Date: 2025-08-27 18:07:13

ethyl 6-fluoro-1-(4-fluorophenyl)-7-(3-methylpiperazin-1-yl)-4-oxo-1,8-naphthyridine-3-carboxylate Structure
ethyl 6-fluoro-1-(4-fluorophenyl)-7-(3-methylpiperazin-1-yl)-4-oxo-1,8-naphthyridine-3-carboxylate structure
 Common Name ethyl 6-fluoro-1-(4-fluorophenyl)-7-(3-methylpiperazin-1-yl)-4-oxo-1,8-naphthyridine-3-carboxylate
CAS Number 100546-84-7 Molecular Weight 428.43200
Density N/A Boiling Point N/A
Molecular Formula C22H22F2N4O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name ethyl 6-fluoro-1-(4-fluorophenyl)-7-(3-methylpiperazin-1-yl)-4-oxo-1,8-naphthyridine-3-carboxylate
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C22H22F2N4O3
Molecular Weight 428.43200
Exact Mass 428.16600
PSA 76.46000
LogP 3.03250

 Synthetic Route

2-Methylpiperazine structure

2-Methylpiperazine

CAS#:109-07-9

ethyl 7-chloro-6-fluoro-1-(4-fluorophenyl)-4-oxo-1,8-naphthyridine-3-carboxylate structure

ethyl 7-chloro-...

CAS#:100491-30-3

~88%

ethyl 6-fluoro-1-(4-fluorophenyl)-7-(3-methylpiperazin-1-yl)-4-oxo-1,8-naphthyridine-3-carboxylate Structure

ethyl 6-fluoro-...

CAS#:100546-84-7

Literature: Chu, Daniel T. W.; Fernandes, Prabhavathi B.; Claiborne, Akiyo K.; Gracey, Eugene H.; Pernet, Andre G. Journal of Medicinal Chemistry, 1986 , vol. 29, # 11 p. 2364 - 2369
Ethyl 2,6-dichloro-5-fluoro-pyridine-3-acetoacetate structure

Ethyl 2,6-dichl...

CAS#:96568-04-6

~%

ethyl 6-fluoro-1-(4-fluorophenyl)-7-(3-methylpiperazin-1-yl)-4-oxo-1,8-naphthyridine-3-carboxylate Structure

ethyl 6-fluoro-...

CAS#:100546-84-7

Literature: Chu, Daniel T. W.; Fernandes, Prabhavathi B.; Claiborne, Akiyo K.; Gracey, Eugene H.; Pernet, Andre G. Journal of Medicinal Chemistry, 1986 , vol. 29, # 11 p. 2364 - 2369
2,6-dichloro-5-fluoronicotinoyl chloride structure

2,6-dichloro-5-...

CAS#:96568-02-4

~%

ethyl 6-fluoro-1-(4-fluorophenyl)-7-(3-methylpiperazin-1-yl)-4-oxo-1,8-naphthyridine-3-carboxylate Structure

ethyl 6-fluoro-...

CAS#:100546-84-7

Literature: Chu, Daniel T. W.; Fernandes, Prabhavathi B.; Claiborne, Akiyo K.; Gracey, Eugene H.; Pernet, Andre G. Journal of Medicinal Chemistry, 1986 , vol. 29, # 11 p. 2364 - 2369
2,6-Dichloro-5-fluoronicotinic acid structure

2,6-Dichloro-5-...

CAS#:82671-06-5

~%

ethyl 6-fluoro-1-(4-fluorophenyl)-7-(3-methylpiperazin-1-yl)-4-oxo-1,8-naphthyridine-3-carboxylate Structure

ethyl 6-fluoro-...

CAS#:100546-84-7

Literature: Chu, Daniel T. W.; Fernandes, Prabhavathi B.; Claiborne, Akiyo K.; Gracey, Eugene H.; Pernet, Andre G. Journal of Medicinal Chemistry, 1986 , vol. 29, # 11 p. 2364 - 2369
ethyl 2,6-dichloro-5-fluoropyridine-3-carboxylate structure

ethyl 2,6-dichl...

CAS#:82671-03-2

~%

ethyl 6-fluoro-1-(4-fluorophenyl)-7-(3-methylpiperazin-1-yl)-4-oxo-1,8-naphthyridine-3-carboxylate Structure

ethyl 6-fluoro-...

CAS#:100546-84-7

Literature: Chu, Daniel T. W.; Fernandes, Prabhavathi B.; Claiborne, Akiyo K.; Gracey, Eugene H.; Pernet, Andre G. Journal of Medicinal Chemistry, 1986 , vol. 29, # 11 p. 2364 - 2369
ethyl 3-p-fluoroanilino-2-(2,6-dichloro-5-fluoronicotinyl)acrylate structure

ethyl 3-p-fluor...

CAS#:100491-00-7

~%

ethyl 6-fluoro-1-(4-fluorophenyl)-7-(3-methylpiperazin-1-yl)-4-oxo-1,8-naphthyridine-3-carboxylate Structure

ethyl 6-fluoro-...

CAS#:100546-84-7

Literature: Chu, Daniel T. W.; Fernandes, Prabhavathi B.; Claiborne, Akiyo K.; Gracey, Eugene H.; Pernet, Andre G. Journal of Medicinal Chemistry, 1986 , vol. 29, # 11 p. 2364 - 2369

 Synonyms

ethyl 1-p-fluorophenyl-6-fluoro-7-(3-methyl-1-piperazinyl)-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylate
ethyl 6-fluoro-1-(4-fluorophenyl)-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate
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Chemsrc provides CAS#:100546-84-7 MSDS, density, melting point, boiling point, structure, etc. Its name is ethyl 6-fluoro-1-(4-fluorophenyl)-7-(3-methylpiperazin-1-yl)-4-oxo-1,8-naphthyridine-3-carboxylate>> amp version: ethyl 6-fluoro-1-(4-fluorophenyl)-7-(3-methylpiperazin-1-yl)-4-oxo-1,8-naphthyridine-3-carboxylate

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