2(3H)-Furanone,dihydro-5-phenyl-

Modify Date: 2024-01-23 20:17:00

2(3H)-Furanone,dihydro-5-phenyl- structure	Common Name	2(3H)-Furanone,dihydro-5-phenyl-
	CAS Number	1008-76-0	Molecular Weight	162.18500
	Density	1.155 g/mL at 25 °C(lit.)	Boiling Point	306 °C(lit.)
	Molecular Formula	C₁₀H₁₀O₂	Melting Point	36-37 °C(lit.)
	MSDS	Chinese USA	Flash Point	>230 °F

Name	gamma-Phenyl-gamma-butyrolactone
Synonym	More Synonyms

Density	1.155 g/mL at 25 °C(lit.)
Boiling Point	306 °C(lit.)
Melting Point	36-37 °C(lit.)
Molecular Formula	C₁₀H₁₀O₂
Molecular Weight	162.18500
Flash Point	>230 °F
Exact Mass	162.06800
PSA	26.30000
LogP	2.06470
Vapour Pressure	0.000793mmHg at 25°C
Index of Refraction	1.5415-1.5435

2(3H)-Furanone,dihydro-5-phenyl- MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LU3690000

CHEMICAL NAME :: 2(3H)-Furanone, 4,5-dihydro-5-phenyl-

CAS REGISTRY NUMBER :: 1008-76-0

BEILSTEIN REFERENCE NO. :: 0125169

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C10-H10-O2

MOLECULAR WEIGHT :: 162.20

WISWESSER LINE NOTATION :: T5OVTJ ER

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex) Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: RCOCB8 Research Communications in Chemical Pathology and Pharmacology. (PJD Pub. Ltd., P.O. Box 966, Westbury, NY 11590) V.1- 1970- Volume(issue)/page/year: 18,439,1977

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi
Safety Phrases	S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	LU3690000
HS Code	2932209090

HS Code	2932209090
Summary	2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Pronounced differences in inhibition potency of lactone and non-lactone compounds for mouse and human coumarin 7-hydroxylases (CYP2A5 and CYP2A6).

Xenobiotica 30(1) , 81-92, (2000)

1. The structural requirements for a compound to be a potent inhibitor for mouse CYP2A5 and human CYP2A6 enzymes catalysing coumarin 7-hydroxylase activity have been studied. 2. The IC50 of 28 compoun...

MFCD00005398

γ-PHENYL-γ-BUTYROLACTONE

EINECS 213-761-0