D-3263 (hydrochloride)
Modify Date: 2024-01-08 01:50:33
D-3263 (hydrochloride) structure
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Common Name | D-3263 (hydrochloride) | ||
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| CAS Number | 1008763-54-9 | Molecular Weight | 409.950 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H32ClN3O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of D-3263 (hydrochloride)D-3263 hydrochloride is an enteric-coated, orally bioavailable (transient receptor potential melastatin member 8) TRPM8 agonist. |
| Name | 3-(2-Aminoethyl)-1-{[(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl]carbonyl}-5-methoxy-1,3-dihydro-2H-benzimidazol-2-one hydrochloride (1:1) |
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| Synonym | More Synonyms |
| Description | D-3263 hydrochloride is an enteric-coated, orally bioavailable (transient receptor potential melastatin member 8) TRPM8 agonist. |
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| Related Catalog | |
| In Vitro | D-3263 hydrochloride binds to and activates TRPM8, which may result in an increase in calcium and sodium entry; the disruption of calcium and sodium homeostasis; and the induction of cell death in TRPM8-expressing tumor cells. D-3263 hydrochloride may decrease dihydrotestosterone (DHT) levels, which may contribute to its inhibitory effects on prostate cancer and BPH[1]. |
| References |
| Molecular Formula | C21H32ClN3O3 |
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| Molecular Weight | 409.950 |
| Exact Mass | 409.213226 |
| Storage condition | 2-8℃ |
| 2H-Benzimidazol-2-one, 3-(2-aminoethyl)-1,3-dihydro-5-methoxy-1-[[(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl]carbonyl]-, hydrochloride (1:1) |
| 3-(2-Aminoethyl)-1-{[(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl]carbonyl}-5-methoxy-1,3-dihydro-2H-benzimidazol-2-one hydrochloride (1:1) |
| D-3263 HCl |
| D-3263 (hydrochloride) |