4,4'-Dimethoxydiphenylamine

Modify Date: 2025-08-26 16:30:00

4,4'-Dimethoxydiphenylamine Structure
4,4'-Dimethoxydiphenylamine structure
Common Name 4,4'-Dimethoxydiphenylamine
CAS Number 101-70-2 Molecular Weight 229.274
Density 1.1±0.1 g/cm3 Boiling Point 371.1±27.0 °C at 760 mmHg
Molecular Formula C14H15NO2 Melting Point 101-102°C
MSDS Chinese USA Flash Point 150.5±13.2 °C
Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Warning

 Names

Name Bis(4-methoxyphenyl)amine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 371.1±27.0 °C at 760 mmHg
Melting Point 101-102°C
Molecular Formula C14H15NO2
Molecular Weight 229.274
Flash Point 150.5±13.2 °C
Exact Mass 229.110275
PSA 30.49000
LogP 2.87
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.593
InChIKey VCOONNWIINSFBA-UHFFFAOYSA-N
SMILES COc1ccc(Nc2ccc(OC)cc2)cc1
Stability Stability Combustible. Incompatible with strong oxidizing agents.

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DU9085000
CHEMICAL NAME :
4-Biphenylamine, 4,4'-dimethoxy-
CAS REGISTRY NUMBER :
101-70-2
LAST UPDATED :
199701
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C14-H15-N-O2
MOLECULAR WEIGHT :
229.30

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2470 mg/kg
TOXIC EFFECTS :
Behavioral - tremor Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - other changes
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2500 mg/kg
TOXIC EFFECTS :
Behavioral - tremor Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - other changes

MUTATION DATA

TYPE OF TEST :
Cytogenetic analysis
TEST SYSTEM :
Rodent - hamster Lung
DOSE/DURATION :
30 mg/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 241,175,1990 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80320 No. of Facilities: 96 (estimated) No. of Industries: 3 No. of Occupations: 15 No. of Employees: 1166 (estimated)

 Safety Information

Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Warning
Hazard Statements H315-H319-H335-H351
Precautionary Statements P261-P281-P305 + P351 + P338
Hazard Codes Xi
Risk Phrases R68
Safety Phrases S22-S36/37/39
RIDADR NONH for all modes of transport
RTECS DU9085000
HS Code 2922299090

 Synthetic Route

 Customs

HS Code 2922299090
Summary 2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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 4,4'-DimethoxydiphenylamineBioassay

View more

Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
Name: qHTS of TDP-43 Inhibitors: NCGC Sytravon Library Screen
Source: NCGC
External Id: tdp43-p2-repeat
Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
Name: Fluorescence polarization-based biochemical high throughput primary assay to identify...
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id: SIAE_INH_FP_1536_1X%INH PRUN
Name: p53 small molecule agonists, cell-based qHTS assay
Source: 824
External Id: P53344
Name: p53 small molecule agonists, cell-based qHTS assay with human liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS233
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 Synonyms

4-Methoxy-N-(4-methoxyphenyl)aniline
Bis-(4-methoxy-phenyl)-amine
Di-p-anisylamine
EINECS 202-968-1
4,4'-Dimethoxydiphenylamine
MFCD00014895
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