nitric oxide

Modify Date: 2024-01-03 00:21:23

nitric oxide Structure
nitric oxide structure
Common Name nitric oxide
CAS Number 10102-43-9 Molecular Weight 30.00610
Density 1.24 g/cmsup>3 Boiling Point −151.7 °C(lit.)
Molecular Formula NO Melting Point −163.6 °C(lit.)
MSDS N/A Flash Point N/A

 Names

Name nitric oxide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.24 g/cmsup>3
Boiling Point −151.7 °C(lit.)
Melting Point −163.6 °C(lit.)
Molecular Formula NO
Molecular Weight 30.00610
Exact Mass 29.99800
PSA 17.07000
Vapour density 1.05 (vs air)
Stability Spontaneously reacts with oxygen in air to yield brown nitrogen dioxide. Reacts violently or explosively with ammonia and many organic materials.

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QX0525000
CHEMICAL NAME :
Nitrogen monoxide
CAS REGISTRY NUMBER :
10102-43-9
LAST UPDATED :
199712
DATA ITEMS CITED :
30
MOLECULAR FORMULA :
N-O
MOLECULAR WEIGHT :
30.01
WISWESSER LINE NOTATION :
N O

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1068 mg/m3/4H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
320 ppm
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - cyanosis Blood - methemoglobinemia-carboxyhemoglobin
TYPE OF TEST :
LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
5000 ppm/25M
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - acute pulmonary edema Blood - methemoglobinemia-carboxyhemoglobin
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
50 mg/m3/6H/7W-I
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - changes in lung weight Liver - changes in liver weight Nutritional and Gross Metabolic - weight loss or decreased weight gain
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3 mg/m3/24H/16D-C
TOXIC EFFECTS :
Brain and Coverings - recordings from specific areas of CNS Blood - methemoglobinemia-carboxyhemoglobin Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
10 ppm/2H/30W-I
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - emphysema Blood - pigmented or nucleated red blood cells Blood - changes in leukocyte (WBC) count
TYPE OF TEST :
Mutation in mammalian somatic cells

MUTATION DATA

TYPE OF TEST :
Mutation in mammalian somatic cells
TEST SYSTEM :
Rodent - hamster Fibroblast
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 136,119,1984 *** REVIEWS *** ACGIH TLV-TWA 31 mg/m3 (25 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 TOXICOLOGY REVIEW CTOXAO Clinical Toxicology. (New York, NY) V.1-18, 1968-81. For publisher information, see JTCTDW. Volume(issue)/page/year: 7,145,1974 TOXICOLOGY REVIEW XPHBAO U.S. Public Health Service, Public Health Bulletin. (Washington, DC) Volume(issue)/page/year: 272,1,1941 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 25 ppm (30 mg/m3) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,182,1971 OSHA PEL (Gen Indu):8H TWA 25 ppm (30 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 25 ppm (30 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 25 ppm (30 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 25 ppm (30 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-THE NETHERLANDS:TWA 25 ppm (30 mg/m3) JAN 1993 OEL-THAILAND:TWA 25 ppm (30 mg/m3) JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO NITRIC OXIDE-air:10H TWA 25 ppm REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 50745 No. of Facilities: 276 (estimated) No. of Industries: 11 No. of Occupations: 11 No. of Employees: 1354 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 50745 No. of Facilities: 59 (estimated) No. of Industries: 3 No. of Occupations: 16 No. of Employees: 14332 (estimated) No. of Female Employees: 6183 (estimated)

 Safety Information

Hazard Codes O,T
Risk Phrases R8
Safety Phrases S17-S23-S36/37/39-S45
RIDADR UN 1660 2.3
WGK Germany 1
RTECS QX0525000
Hazard Class 2.3

 Synonyms

oxido nitrico
MFCD00011525
NITRIC OXIDE
oxyde azotique
INOmax
oxoazanyl
Stickstoffmonoxid
Mononitrogen monoxide
EINECS 233-271-0
nitrosyl
nitrogen monooxide
Nitrosyl radical