2'-Chloro-2'-deoxycytidine

Modify Date: 2024-01-21 01:13:34

2'-Chloro-2'-deoxycytidine Structure
2'-Chloro-2'-deoxycytidine structure
 Common Name 2'-Chloro-2'-deoxycytidine
CAS Number 10212-19-8 Molecular Weight 261.66
Density 1.9±0.1 g/cm3 Boiling Point 551.3±60.0 °C at 760 mmHg
Molecular Formula C9H12ClN3O4 Melting Point N/A
MSDS N/A Flash Point 287.2±32.9 °C

 Use of 2'-Chloro-2'-deoxycytidine


2-Chloro-2'-deoxycytidine is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].

 Names

Name 4-amino-1-[(2R,3R,4R,5R)-3-chloro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
Synonym More Synonyms

 2'-Chloro-2'-deoxycytidine Biological Activity

Description 2-Chloro-2'-deoxycytidine is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].
Related Catalog
References

[1]. Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8.  

 Chemical & Physical Properties

Density 1.9±0.1 g/cm3
Boiling Point 551.3±60.0 °C at 760 mmHg
Molecular Formula C9H12ClN3O4
Molecular Weight 261.66
Flash Point 287.2±32.9 °C
Exact Mass 261.051636
PSA 110.60000
LogP -1.43
Vapour Pressure 0.0±3.4 mmHg at 25°C
Index of Refraction 1.736

 Synonyms

Cytidine,2'-chloro-2'-deoxy-(8CI,9CI)
2'-Chlor-2'-deoxycytidin
2'-Chloro-2'-deoxycytidine
2'-Chlor-2'-desoxy-cytidin
Cytidine, 2'-chloro-2'-deoxy-
2'-chloro-2'-deoxy-cytidine
2'-Deoxy-2'-chlorocytidine
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Chemsrc provides 2'-Chloro-2'-deoxycytidine(CAS#:10212-19-8) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of 2'-Chloro-2'-deoxycytidine are included as well.>> amp version: 2'-Chloro-2'-deoxycytidine

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