10212-19-8

10212-19-8 structure

Name: 2'-Chloro-2'-deoxycytidine
Chemical Name: 4-amino-1-[(2R,3R,4R,5R)-3-chloro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
CAS Number: 10212-19-8
Molecular Formula: C₉H₁₂ClN₃O₄
Molecular Weight: 261.66
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-09-15 17:05:25
Modify Date: 2024-01-21 01:13:34
2-Chloro-2'-deoxycytidine is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].

Name	4-amino-1-[(2R,3R,4R,5R)-3-chloro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
Synonyms	Cytidine,2'-chloro-2'-deoxy-(8CI,9CI) 2'-Chlor-2'-deoxycytidin 2'-Chloro-2'-deoxycytidine 2'-Chlor-2'-desoxy-cytidin Cytidine, 2'-chloro-2'-deoxy- 2'-chloro-2'-deoxy-cytidine 2'-Deoxy-2'-chlorocytidine

Description	2-Chloro-2'-deoxycytidine is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8.