Heptachlor epoxide [Isomer B]

Modify Date: 2024-01-02 14:19:43

Heptachlor epoxide [Isomer B] structure	Common Name	Heptachlor epoxide [Isomer B]
	CAS Number	1024-57-3	Molecular Weight	389.317
	Density	1.9±0.1 g/cm3	Boiling Point	425.5±45.0 °C at 760 mmHg
	Molecular Formula	C₁₀H₅Cl₇O	Melting Point	160-161.5℃
	MSDS	Chinese USA	Flash Point	162.2±28.8 °C
	Symbol	GHS06, GHS08	Signal Word	Danger

Use of Heptachlor epoxide [Isomer B]

(±)-cis-Heptachlor epoxides, are degradation products of heptachlor that can occur in or on soil and crops when treated with heptachlor, a pesticide. Heptachlor is readily formed upon exposure to air. Everett CJ, Thompson OM. Environmental Health Pastor. 2015;30(2):93-7.

Name	Heptachlor epoxide [Isomer B]
Synonym	More Synonyms

Description	(±)-cis-Heptachlor epoxides, are degradation products of heptachlor that can occur in or on soil and crops when treated with heptachlor, a pesticide. Heptachlor is readily formed upon exposure to air. Everett CJ, Thompson OM. Environmental Health Pastor. 2015;30(2):93-7.
Related Catalog	Research Areas >> Others

Density	1.9±0.1 g/cm3
Boiling Point	425.5±45.0 °C at 760 mmHg
Melting Point	160-161.5℃
Molecular Formula	C₁₀H₅Cl₇O
Molecular Weight	389.317
Flash Point	162.2±28.8 °C
Exact Mass	385.816010
PSA	12.53000
LogP	5.47
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.662
Storage condition	APPROX 4°C

Heptachlor epoxide [Isomer B] MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: PB9450000

CHEMICAL NAME :: 4,7-Methanoindan, 1,4,5,6,7,8,8-heptachloro-2,3-epoxy-3a,4,7,7a-tetrahy dro-

CAS REGISTRY NUMBER :: 1024-57-3

LAST UPDATED :: 199712

DATA ITEMS CITED :: 25

MOLECULAR FORMULA :: C10-H5-Cl7-O

MOLECULAR WEIGHT :: 389.30

WISWESSER LINE NOTATION :: T D3 C555 A EO JUTJ AG AG BG GG IG JG KG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 15 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 39 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 10 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intracerebral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 8 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 144 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - cattle

DOSE/DURATION :: 5 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Nutritional and Gross Metabolic - body temperature increase

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 580 mg/kg/69W-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 876 mg/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors

MUTATION DATA

TYPE OF TEST :: Unscheduled DNA synthesis

TEST SYSTEM :: Human Fibroblast

DOSE/DURATION :: 10 umol/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 42,161,1977 *** REVIEWS *** ACGIH TLV-Animal carcinogen DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-TWA 0.05 mg/m3 (skin) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 20,129,1979 IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 53,115,1991 IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 5,173,1974 IARC Cancer Review:Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 20,129,1979 IARC Cancer Review:Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 53,115,1991 IARC Cancer Review:Group 2B IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 53,115,1991 TOXICOLOGY REVIEW CTOXAO Clinical Toxicology. (New York, NY) V.1-18, 1968-81. For publisher information, see JTCTDW. Volume(issue)/page/year: 13,231,1978

Symbol	GHS06, GHS08
Signal Word	Danger
Hazard Statements	H301 + H311 + H331-H370-H412
Precautionary Statements	P260-P273-P280-P301 + P310-P311
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US)
Hazard Codes	T,N,F
Risk Phrases	25-33-40-50/53-39/23/24/25-23/24/25-11
Safety Phrases	S7;S16;S45;S60;S61;S36/S37
RIDADR	UN 2761
RTECS	PB9450000
Packaging Group	II
Hazard Class	6.1(a)

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MFCD01311793

Heptachlor expoxide isomer B

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1,6,8,9,10,11,11-Heptachloro-4-oxatetracyclo[6.2.1.0.0]undec-9-ene

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HEPTACHLOR EPOXIDE

2,5-Methano-2H-indeno[1,2-b]oxirene, 2,3,4,5,6,7,7-heptachloro-1a,1b,5,5a,6,6a-hexahydro-

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EINECS 213-831-0